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dasatinib-induced hemorrhagic colitis

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#1 gerry


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Posted 19 January 2017 - 08:44 PM

Fecal occult blood test 'useful' for detecting dasatinib-induced hemorrhagic colitis

medwireNews: Japanese researchers say that a fecal occult blood test could help screen for treatment-induced hemorrhagic colitis in chronic myeloid leukemia (CML) patients taking dasatinib.

They believe it could be "a useful, non-invasive screening test", with the diagnosis confirmed by colonoscopy and pathologic analysis.

Among 30 CML patients who had received a tyrosine kinase inhibitor for at least 1 month - nilotinib in five patients, imatinib in seven, and dasatinib in 18 - 10 had a positive fecal occult blood test. All 10 patients had received dasatinib, and none exhibited clinically relevant symptoms.


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