Posted 10 November 2016 - 12:17 AM
Generic Imatinib Mesylate is becoming very attractive to seniors, such as myself, who are on Medicare. On Medicare, seniors are required to pay a percentage of their drug costs. If a senior is on an expensive patented drug, that first Rx refill of the year is a very expensive proposition. On Medicare, if I was taking a patented TKI, for the first refill of the year in 2017 I would be paying 33% of the first $3700, 40% of the next $1,250 (the donut hole), and with Kaiser, $12 in the catastrophic phase. Once a senior clears the donut hole, for most Medicare patients the rest of his/her refills for the calendar year, while in the catastrophic phase, will still be 5% of the Rx cost.
As I have mentioned before, for 2017, Kaiser has classified generic imatinib mesylate as a Tier 2 drug, requiring Medicare patients only a $15 copay per monthly refill; a total of $180 for the calendar year. At least that is what it says in the booklet.
For the benefit of yourself and others please add your CML history into your Signature
02/2010 Gleevec 400mg
2011 Two weakly positives, PCRU, weakly positive
2012 PCRU, PCRU, PCRU, PCRU
2013 PCRU, PCRU, PCRU, weakly positive
2014 PCRU, PCRU, PCRU, PCRU (12/07 began dose reduction w/each continuing PCRU)
2015 300, 250, 200, 150
2016 100, 50/100, 100, 10/17 TFR
2017 01/17 TFR, 04/18 TFR, 07/18 TFR 0.0012, 08/29 TFR 0.001, 10/17 TFR 0.000
2018 01/16 TFR 0.0004 ... next quarterly PCR 04/17
At the earliest opportunity, and whenever possible, lower your TKI dosage; TKIs are toxic drugs and the less we take longterm the better off we are going to be ... this is especially true for older adults.
In hindsight I should have started my dosage reduction two years earlier; it might have helped minimize some of the longterm cumulative toxic effects of TKIs that I am beset with.
longterm side-effects Peripheral Artery Disease - legs (it's a bitch); continuing shoulder problems, right elbow inflammation. GFR and creatinine vastly improved after stopping Gleevec.
Cumulative Gleevec dosage estimated at 830 grams
Taking Gleevec 400mg an hour after my largest meal of the day helped eliminate the nausea that Gleevec is notorious for.
Trey's CML Blog - Stopping - The Odds - Stop Studies - Discussion Forum Cessation Study
Big PhRMA - Medicare Status - Social Security Status - Deficit/Debt