Advanced Member
Posted 27 October 2016 - 08:47 AM
Just stumbled on this article from May by Dr. Kantarjian, found it interesting and couldn't find any earlier posts on it so thought I would share. Some good info and history into why drug prices are kept high.
The Arrival of Generic Imatinib Into the U.S. Market: An Educational Event
http://www.ascopost....cational-event/
08/2015 Initial PCR: 66.392%
12/2015 PCR: 1.573%
03/2016 PCR: 0.153%
06/2016 PCR: 0.070%
09/2016 PCR: 0.052%
12/2016 PCR: 0.036%
03/2017 PCR: 0.029%
06/2017 PCR: 0.028%
09/2017 PCR: 0.025%
12/2017 PCR: 0.018%
Taking Imatinib 400 mg
Advanced Member
Posted 27 October 2016 - 09:58 AM
The 180 day exclusivity period for Sun is over. We are starting to see new generics by Teva and Apotex on the market. I have read they all have an agreement to keep prices over 50% of where they are now. Not sure how they get away with this. Isn't this price fixing? Once more generics are available we will see prices start to drop. Once a couple of the 2nd gen drugs go generic prices will really start to drop and profits will drop. I realize all this is still 9 to 10 years away. But at that point there should be a lot of competition to come out with a better drug so they can reap the profits again.
Hang in there I firmly believe we will have either a new low side effect drug or cure in 10 to 15 years. It is the only way companies can keep reaping the profits.
10/01/2014 100% Diagnosis (WBC 278k, Blasts 6%, Spleen extended 20cm)
Cancer Sucks!
Advanced Member
Posted 27 October 2016 - 11:16 AM
Absolutely ridiculous that the generic is that much when it costs them $159 per year (400 mg, from the article) to make it. The companies that make the generic have no excuses whatsoever on this, not that the Big Pharmaceuticals excuses were really ever valid. That is plain and simple profiteering at its worst on their part.
As for the price collusion, it is a Drug Cartel.
08/2015 Initial PCR: 66.392%
12/2015 PCR: 1.573%
03/2016 PCR: 0.153%
06/2016 PCR: 0.070%
09/2016 PCR: 0.052%
12/2016 PCR: 0.036%
03/2017 PCR: 0.029%
06/2017 PCR: 0.028%
09/2017 PCR: 0.025%
12/2017 PCR: 0.018%
Taking Imatinib 400 mg
Advanced Member
Posted 27 October 2016 - 11:41 AM
If the below is accurate, it does appear that the generic price is going down.
Brand
https://www.drugs.co...e-guide/gleevec
Generic
https://www.drugs.co...l-tablet-400-mg
Hope Dr. Kantarjian is right and it will be down to $1,000 per year in two years, I really want to switch back to my CDP plan at work, would save me a bundle.
For those on the generic, have you signed up for the $0 copay card?
http://www.imatinibr...stance-program/
08/2015 Initial PCR: 66.392%
12/2015 PCR: 1.573%
03/2016 PCR: 0.153%
06/2016 PCR: 0.070%
09/2016 PCR: 0.052%
12/2016 PCR: 0.036%
03/2017 PCR: 0.029%
06/2017 PCR: 0.028%
09/2017 PCR: 0.025%
12/2017 PCR: 0.018%
Taking Imatinib 400 mg
Member
Posted 04 November 2016 - 03:08 AM
Advanced Member
Posted 04 November 2016 - 12:18 PM
Noticed in my monthly health benefits that the price of the generic imatinib dropped substantially. I want to say it was about 2-3K less.
Advanced Member
Posted 04 November 2016 - 05:08 PM
Noticed in my monthly health benefits that the price of the generic imatinib dropped substantially. I want to say it was about 2-3K less.
MACELPatient, if and when you have a chance could you let us know the price and manufacturer ... thanks in advance.
For the benefit of yourself and others please add your CML history into your Signature
02/2010 Gleevec 400mg
2011 Two weakly positives, PCRU, weakly positive
2012 PCRU, PCRU, PCRU, PCRU
2013 PCRU, PCRU, PCRU, weakly positive
2014 PCRU, PCRU, PCRU, PCRU (12/07 began dose reduction w/each continuing PCRU)
2015 300, 250, 200, 150
2016 100, 50/100, 100, 10/17 TFR
2017 01/17 TFR, 04/18 TFR, 07/18 TFR 0.0012, 08/29 TFR 0.001, 10/17 TFR 0.000
2018 01/16 TFR 0.0004 ... next quarterly PCR 04/17
At the earliest opportunity, and whenever possible, lower your TKI dosage; TKIs are toxic drugs and the less we take longterm the better off we are going to be ... this is especially true for older adults.
In hindsight I should have started my dosage reduction two years earlier; it might have helped minimize some of the longterm cumulative toxic effects of TKIs that I am beset with.
longterm side-effects Peripheral Artery Disease - legs (it's a bitch); continuing shoulder problems, right elbow inflammation. GFR and creatinine vastly improved after stopping Gleevec.
Cumulative Gleevec dosage estimated at 830 grams
Taking Gleevec 400mg an hour after my largest meal of the day helped eliminate the nausea that Gleevec is notorious for.
Trey's CML Blog - Stopping - The Odds - Stop Studies - Discussion Forum Cessation Study
Big PhRMA - Medicare Status - Social Security Status - Deficit/Debt
Advanced Member
Posted 04 November 2016 - 07:39 PM
Advanced Member
Posted 05 November 2016 - 08:18 AM
Sun Pharma
$44.60/per pill
$4,014.19 for 30 day/ 300mg per day.
Insurance in MA covers 100% by law.
Thanks MACELPatient. Good to see the price coming down; a real bargain as compared to the price of Gleevec 100 mg, which was well north of $100 per the last time I checked. But, considering the price in Canada, and elsewhere, there is still a long way to go.
For the benefit of yourself and others please add your CML history into your Signature
02/2010 Gleevec 400mg
2011 Two weakly positives, PCRU, weakly positive
2012 PCRU, PCRU, PCRU, PCRU
2013 PCRU, PCRU, PCRU, weakly positive
2014 PCRU, PCRU, PCRU, PCRU (12/07 began dose reduction w/each continuing PCRU)
2015 300, 250, 200, 150
2016 100, 50/100, 100, 10/17 TFR
2017 01/17 TFR, 04/18 TFR, 07/18 TFR 0.0012, 08/29 TFR 0.001, 10/17 TFR 0.000
2018 01/16 TFR 0.0004 ... next quarterly PCR 04/17
At the earliest opportunity, and whenever possible, lower your TKI dosage; TKIs are toxic drugs and the less we take longterm the better off we are going to be ... this is especially true for older adults.
In hindsight I should have started my dosage reduction two years earlier; it might have helped minimize some of the longterm cumulative toxic effects of TKIs that I am beset with.
longterm side-effects Peripheral Artery Disease - legs (it's a bitch); continuing shoulder problems, right elbow inflammation. GFR and creatinine vastly improved after stopping Gleevec.
Cumulative Gleevec dosage estimated at 830 grams
Taking Gleevec 400mg an hour after my largest meal of the day helped eliminate the nausea that Gleevec is notorious for.
Trey's CML Blog - Stopping - The Odds - Stop Studies - Discussion Forum Cessation Study
Big PhRMA - Medicare Status - Social Security Status - Deficit/Debt
Advanced Member
Posted 05 November 2016 - 08:26 AM
I heard yesterday on NPR that the justice department is investigating drug companies that they feel are colluding.
http://www.wsj.com/a...robe-1478209036
They don't say which companies at this point, though.
Pat
"You can't change the direction of the wind but you can adjust your sails."
DX 12/08; Gleevec 400mg; liver toxicity; Sprycel 100mg.; CCyR 4/10; MMR 8/10; Pleural Effusion 2/12; Sprycel 50mg. Maintaining MMR; 2/15 PCRU; 8/16 drifting in and out of undetected like a wave meeting the shore. Retired 12/23/2016! 18 months of PCRU, most recent at Mayo on 7/25/17 was negative at their new sensitivity reporting of 0.003.<p>
Advanced Member
Posted 05 November 2016 - 08:40 AM
I heard yesterday on NPR that the justice department is investigating drug companies that they feel are colluding.
http://www.wsj.com/a...robe-1478209036
They don't say which companies at this point, though.
Hi Pat, I saw a list of the numerous companies being investigated/receiving subpoenas; Sun and Teva were included .. I don't know that they were included in regard to the pricing of generic Imatinib. Collusion on drug pricing appears to be widespread.
For the benefit of yourself and others please add your CML history into your Signature
02/2010 Gleevec 400mg
2011 Two weakly positives, PCRU, weakly positive
2012 PCRU, PCRU, PCRU, PCRU
2013 PCRU, PCRU, PCRU, weakly positive
2014 PCRU, PCRU, PCRU, PCRU (12/07 began dose reduction w/each continuing PCRU)
2015 300, 250, 200, 150
2016 100, 50/100, 100, 10/17 TFR
2017 01/17 TFR, 04/18 TFR, 07/18 TFR 0.0012, 08/29 TFR 0.001, 10/17 TFR 0.000
2018 01/16 TFR 0.0004 ... next quarterly PCR 04/17
At the earliest opportunity, and whenever possible, lower your TKI dosage; TKIs are toxic drugs and the less we take longterm the better off we are going to be ... this is especially true for older adults.
In hindsight I should have started my dosage reduction two years earlier; it might have helped minimize some of the longterm cumulative toxic effects of TKIs that I am beset with.
longterm side-effects Peripheral Artery Disease - legs (it's a bitch); continuing shoulder problems, right elbow inflammation. GFR and creatinine vastly improved after stopping Gleevec.
Cumulative Gleevec dosage estimated at 830 grams
Taking Gleevec 400mg an hour after my largest meal of the day helped eliminate the nausea that Gleevec is notorious for.
Trey's CML Blog - Stopping - The Odds - Stop Studies - Discussion Forum Cessation Study
Big PhRMA - Medicare Status - Social Security Status - Deficit/Debt
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Gleevec Generic Price is inStarted by r06ue1 , 11 Feb 2016 Gleevec, Generic, Price
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Gleevec Generic Price is inStarted by r06ue1 , 11 Feb 2016 Gleevec, Generic, Price
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