2016 PCR results are:
Jan - 0.08 local lab
Mar - 0.04 MDA lab from bone marrow
Apr - 0.14 local lab
May - 0.195 local lab
Jun - 0.07 MDA lab PB from kit sent in
Jul - 0.03 local lab
Sep 13 - 0.16 MDA PB from kit sent in
Sep 26 - 0.31 MDA PB there at MDA.
Thanks for the article. Although CyCR is the gold standard, there's still discussion on what it means when PCR moves up or down, especially in us turtles. On 9/21/15, chromosome test showed one positive for PH+ plus der(1;7). Interesting enough in Mar of 2016, the chromosome test came back negative, but it was only 14/14 and no der(1:7). Since I didn't get a bone marrow at this visit (first time ever!), these test weren't ran.
You can see the PCR's from above and of course I have results from previous years too, but I thought I was pretty stable and always trending down since reaching CyCR in Aug 2014, except for that one positive chromosome in Sep of last year.
It was Dr Cortes that said the 9/13 sample was probably degraded, something about the enzyme not being good enough. Evidently, they ran it anyway after they had called looking for it. The lab had told the team that they didn't have results from this draw at the time of the appointment on the morning of the 26th.
I had a regular blood draw for CBC and chemistries on the evening of the 25th. Then after my appointment on the 26th, around 11:00 am, they did another blood draw for the PCR test as well as another round of CBC and chemistries. Even the numbers for the CBC were really different between the two draws. You've always said how different they can be even on the same sample, and boy were you right!
Can hardly wait to see what my insurance says about all these test! I see a big bill headed my way!
Dx - 05/2011; PCR: 15.04; Fish: 87% Slow responder due to pancytopenia. Current - Bosulif - Nov: 2012, Mar 2016 lowered to 300 mg. 07/16 back to 400 mg. Clinical trial drug, Promacta, Feb 2013, for low Platelets.
CyCR - Aug 2014, Positive for 1 chromosome Sep 2015. PCR: 12.77 in Oct, 2012 to 0.04 (MDA) in Mar, 2016. 4/2016 - 0.126 (Local lab (IS); 05/2016 - 0.195 (local); 6/2016 - 0.07 (MDA); 7/2016 - 0.03 (local) 9/13/2016 - 0.16 (MDA); 9/26/2016 - 0.31 (MDA); 11/2016 - 0.012 (local); 01/2017 - 0.24 (MDA); 04/2017 - 0.09 (MDA); Cytogenetics show der(1:7)(q10;p10)7 chromosome mutation. Repeat of Sep 2015. PCR - 6/2017- 0.035 (local); 10/2017- 0.02 (MDA)