Advanced Member
Posted 10 September 2016 - 07:15 PM
What happens to the research animals that were tested with the various TKIs in clinical trials? Are they destroyed afterwards, observed outside of clinical trials for residual effects, or anything else?
Maybe I'm having a bit of survivor guilt. Can I adopt one of these animals? 
And, just remembered, I actually took up donations for "Send a Mouse to College" many moons ago. I was duped.
Advanced Member
Posted 10 September 2016 - 07:42 PM
What happens to the research animals that were tested with the various TKIs in clinical trials? Are they destroyed afterwards, observed outside of clinical trials for residual effects, or anything else?
Maybe I'm having a bit of survivor guilt. Can I adopt one of these animals?
Diagnosed 11 May 2011 (100% FiSH, 155% PCR)
with b2a2 BCR-ABL fusion transcript coding for the 210kDa BCR-ABL protein
Sprycel: 20 mg per day - taken at lights out with Quercetin and/or Magnesium Taurate
6-8 grams Curcumin C3 complex.
2015 PCR: < 0.01% (M.D. Anderson scale)
2016 PCR: < 0.01% (M.D. Anderson scale)
March 2017 PCR: 0.01% (M.D. Anderson scale)
June 2017 PCR: "undetected"
September 2017 PCR: "undetected"
Advanced Member
Posted 10 September 2016 - 11:08 PM
Advanced Member
Posted 11 September 2016 - 12:15 PM
Research studies on mice show they volunteer for CML research and are glad to do so. One mouse said "It is indeed a great honour to support the critical research needed to develop new targeted therapies which will help our fellow earthlings, even though humans are lesser creatures." That mouse died shortly thereafter from strangulation by a lab worker who heard the interview. But the sentiment was nice, I think.
Advanced Member
Posted 11 September 2016 - 03:06 PM
Diagnosed 11 May 2011 (100% FiSH, 155% PCR)
with b2a2 BCR-ABL fusion transcript coding for the 210kDa BCR-ABL protein
Sprycel: 20 mg per day - taken at lights out with Quercetin and/or Magnesium Taurate
6-8 grams Curcumin C3 complex.
2015 PCR: < 0.01% (M.D. Anderson scale)
2016 PCR: < 0.01% (M.D. Anderson scale)
March 2017 PCR: 0.01% (M.D. Anderson scale)
June 2017 PCR: "undetected"
September 2017 PCR: "undetected"
Advanced Member
Posted 12 September 2016 - 10:35 AM
lol Trey
08/2015 Initial PCR: 66.392%
12/2015 PCR: 1.573%
03/2016 PCR: 0.153%
06/2016 PCR: 0.070%
09/2016 PCR: 0.052%
12/2016 PCR: 0.036%
03/2017 PCR: 0.029%
06/2017 PCR: 0.028%
09/2017 PCR: 0.025%
12/2017 PCR: 0.018%
Taking Imatinib 400 mg
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