Posted 22 September 2016 - 09:40 PM
Dec. 2014 0.72%
Feb. 2015 0.67%
Apr. 2015 0.42%
May. 2015 0.45%
Jun. 2015 0.35%
Jul. 2015 0.24%
Aug. 2015 0.22%
Sep. 2015 0.18%
Nov. 2015 0.18%
Jan. 2016 0.18%
Feb. 2016 0.11%
Mar. 2016 0.13%
May 2016 0.07%
Jul 2016 0.17%
Sep 2016 0.12%
Buzzm1, rcase13 and Everyone, I received my PCR result from September 12/16, it is 0.12%. It was 0.07% went up to 0.17%, but now it is 0.12%. Thank you all for the support!!
acl
acl, a 10 day turnaround on your PCR result is a vast improvement over 52 days but you are still wrestling with the same problem, a very slow response; it's between you and your oncologist whether you switch to a lowered dose of Sprycel ...
For the benefit of yourself and others please add your CML history into your Signature
02/2010 Gleevec 400mg
2011 Two weakly positives, PCRU, weakly positive
2012 PCRU, PCRU, PCRU, PCRU
2013 PCRU, PCRU, PCRU, weakly positive
2014 PCRU, PCRU, PCRU, PCRU (12/07 began dose reduction w/each continuing PCRU)
2015 300, 250, 200, 150
2016 100, 50/100, 100, 10/17 TFR
2017 01/17 TFR, 04/18 TFR, 07/18 TFR 0.0012, 08/29 TFR 0.001, 10/17 TFR 0.000
2018 01/16 TFR 0.0004 ... next quarterly PCR 04/17
At the earliest opportunity, and whenever possible, lower your TKI dosage; TKIs are toxic drugs and the less we take longterm the better off we are going to be ... this is especially true for older adults.
In hindsight I should have started my dosage reduction two years earlier; it might have helped minimize some of the longterm cumulative toxic effects of TKIs that I am beset with.
longterm side-effects Peripheral Artery Disease - legs (it's a bitch); continuing shoulder problems, right elbow inflammation. GFR and creatinine vastly improved after stopping Gleevec.
Cumulative Gleevec dosage estimated at 830 grams
Taking Gleevec 400mg an hour after my largest meal of the day helped eliminate the nausea that Gleevec is notorious for.
Trey's CML Blog - Stopping - The Odds - Stop Studies - Discussion Forum Cessation Study
Big PhRMA - Medicare Status - Social Security Status - Deficit/Debt