http://www.cnbc.com/...r=yahoo&ref=yfp
Wonder if I could adapt to new Zealand;)
just another article about the cost of gleevec in comparison to other countries
Started by
Frogiegirl
, Aug 21 2016 09:35 PM
21 replies to this topic
#1
Frogiegirl
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Posted 21 August 2016 - 09:35 PM
Diagnosed Oct 2013 Started 600mg of Tasigna on Nov 4th. Lowered dose a few months later to 300mg due to side affects stayed here declining PCR until March 2015 small jump from 0.0072 to 0.0083 scarred my doc into full dose of Tasigna again 600mg(been miserable since) but reached PCRU 06/15/2015(next test) and have been there ever since. Hoping to have another little one. I have the support of my doc to go off anytime, just scared to jump. might go two years PCRU but he said it wont make much of a difference. I just figured I could possibly go into a trial while preggers if I got the two years behind me.
Nov 8th 2017 went off Tasigna
Dec 1st PCRU off TKI
Jan 5th PCR Detected .0625
Feb 1st PCR Detected .7815
Added 8-6 grams Curcumin daily in Feb
March 3rd PCR Detected 3.2646 YIKES!
stopped trying for baby after February reading. will start new TKI march 16th 2017 (Sprycel)
FYI I'm not done trying for my last little one.
#2
Buzzm1
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Posted 21 August 2016 - 09:56 PM
http://www.cnbc.com/...r=yahoo&ref=yfp
Wonder if I could adapt to new Zealand;)
From the article:
"Ultimately, it means Americans are bearing a higher cost for prescription drugs than many other countries. For example, the price for cancer drug Gleevec is $989 in New Zealand, compared to $6,214 in the U.S., according to the International Federation of Health Plans."
Is this what is referred to as literary license? Gleevec isn't priced anywhere near $6,214.
I sent the author a note.
For the benefit of yourself and others please add your CML history into your Signature
02/2010 Gleevec 400mg
2011 Two weakly positives, PCRU, weakly positive
2012 PCRU, PCRU, PCRU, PCRU
2013 PCRU, PCRU, PCRU, weakly positive
2014 PCRU, PCRU, PCRU, PCRU (12/07 began dose reduction w/each continuing PCRU)
2015 300, 250, 200, 150
2016 100, 50/100, 100, 10/17 TFR
2017 01/17 TFR, 04/18 TFR, 07/18 TFR 0.0012, 08/29 TFR 0.001, 10/17 TFR 0.000
2018 01/16 TFR 0.0004 ... next quarterly PCR 04/17
At the earliest opportunity, and whenever possible, lower your TKI dosage; TKIs are toxic drugs and the less we take longterm the better off we are going to be ... this is especially true for older adults.
In hindsight I should have started my dosage reduction two years earlier; it might have helped minimize some of the longterm cumulative toxic effects of TKIs that I am beset with.
longterm side-effects Peripheral Artery Disease - legs (it's a bitch); continuing shoulder problems, right elbow inflammation. GFR and creatinine vastly improved after stopping Gleevec.
Cumulative Gleevec dosage estimated at 830 grams
Taking Gleevec 400mg an hour after my largest meal of the day helped eliminate the nausea that Gleevec is notorious for.
Trey's CML Blog - Stopping - The Odds - Stop Studies - Discussion Forum Cessation Study
Big PhRMA - Medicare Status - Social Security Status - Deficit/Debt
#3
gerry
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Posted 22 August 2016 - 12:03 AM
Even with government negotiation, hard to believe it would be that low in NZ. Would have to check my Gleevec box for accurate price, but it was around $3500 in Australia.
#4
gerry
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Posted 22 August 2016 - 12:07 AM
Perhaps that is the yearly cost following taxpayer subsidy
#5
Buzzm1
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Posted 22 August 2016 - 12:29 AM
Even with government negotiation, hard to believe it would be that low in NZ. Would have to check my Gleevec box for accurate price, but it was around $3500 in Australia.
The prices were obtained from a 2013 International Federation of Health Plans article which means the prices could be from 2012.
For the benefit of yourself and others please add your CML history into your Signature
02/2010 Gleevec 400mg
2011 Two weakly positives, PCRU, weakly positive
2012 PCRU, PCRU, PCRU, PCRU
2013 PCRU, PCRU, PCRU, weakly positive
2014 PCRU, PCRU, PCRU, PCRU (12/07 began dose reduction w/each continuing PCRU)
2015 300, 250, 200, 150
2016 100, 50/100, 100, 10/17 TFR
2017 01/17 TFR, 04/18 TFR, 07/18 TFR 0.0012, 08/29 TFR 0.001, 10/17 TFR 0.000
2018 01/16 TFR 0.0004 ... next quarterly PCR 04/17
At the earliest opportunity, and whenever possible, lower your TKI dosage; TKIs are toxic drugs and the less we take longterm the better off we are going to be ... this is especially true for older adults.
In hindsight I should have started my dosage reduction two years earlier; it might have helped minimize some of the longterm cumulative toxic effects of TKIs that I am beset with.
longterm side-effects Peripheral Artery Disease - legs (it's a bitch); continuing shoulder problems, right elbow inflammation. GFR and creatinine vastly improved after stopping Gleevec.
Cumulative Gleevec dosage estimated at 830 grams
Taking Gleevec 400mg an hour after my largest meal of the day helped eliminate the nausea that Gleevec is notorious for.
Trey's CML Blog - Stopping - The Odds - Stop Studies - Discussion Forum Cessation Study
Big PhRMA - Medicare Status - Social Security Status - Deficit/Debt
#6
gerry
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Posted 22 August 2016 - 01:44 AM
The prices were obtained from a 2013 International Federation of Health Plans article which means the prices could be from 2012.
Still think it might be what they pay after tax payer subsidy - yearly costs for me were around $420.
#7
Sandrea
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Posted 22 August 2016 - 02:51 PM
... Americans are bearing a higher cost for prescription drugs than many other countries ...
All patients in our country get Generic Imatinib is free, but when I get my drug at the pharmacy, I see the price - in July it was 258 rubles (abt $4) for box (filahromin, 120 capsules of 100 mg). But, If you want to buy (for example, CML patient from another country), here is the average price - 3224 rubles (abt $50) for box with monthly dose: http://lekprice.ru/l...a/filahromin-fs
Diagnosed 1 April 2015. WBC 86000; b2a2 (p210) transcript
on Hydrea for 2 months, then generic Gleevec 400mg (06/06/15)
CCyR in April 2016
12/22/2016 PCR: 0.49% (IS) 18 Month
03/29/2017 PCR: 0.68% (not IS) 21 Month
06/06/2017 PCR: 1.62% (not IS) 24 Month
06/20/2017 increased dose of imatinib to 600mg
10/30/2017 PCR: 0.15% (not IS) 28 Month
#8
chriskuo
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Posted 23 August 2016 - 02:37 PM
Today, the mainstream media (including right-wing Fox) has been pounding Mylan hard for the price increases on EpiPen for food allergies (from $100 to $500 since 2008).
LLS should hire the PR people from the anti-Mylan campaign to publicize the price increases of generic imatinib.
#9
Buzzm1
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Posted 23 August 2016 - 07:13 PM
Novartis inched up the price of Gleevec again; I did a price check at Kaiser and was quoted $11,371 for a 30 X 400mg Rx; that works out to a little over $138K/yr.. an increase of about $6K/yr. over the previous $132K/yr..
The price of generic Imatinib mesylate from Sun, Teva, and Apotex, still remains mostly a question.
For the benefit of yourself and others please add your CML history into your Signature
02/2010 Gleevec 400mg
2011 Two weakly positives, PCRU, weakly positive
2012 PCRU, PCRU, PCRU, PCRU
2013 PCRU, PCRU, PCRU, weakly positive
2014 PCRU, PCRU, PCRU, PCRU (12/07 began dose reduction w/each continuing PCRU)
2015 300, 250, 200, 150
2016 100, 50/100, 100, 10/17 TFR
2017 01/17 TFR, 04/18 TFR, 07/18 TFR 0.0012, 08/29 TFR 0.001, 10/17 TFR 0.000
2018 01/16 TFR 0.0004 ... next quarterly PCR 04/17
At the earliest opportunity, and whenever possible, lower your TKI dosage; TKIs are toxic drugs and the less we take longterm the better off we are going to be ... this is especially true for older adults.
In hindsight I should have started my dosage reduction two years earlier; it might have helped minimize some of the longterm cumulative toxic effects of TKIs that I am beset with.
longterm side-effects Peripheral Artery Disease - legs (it's a bitch); continuing shoulder problems, right elbow inflammation. GFR and creatinine vastly improved after stopping Gleevec.
Cumulative Gleevec dosage estimated at 830 grams
Taking Gleevec 400mg an hour after my largest meal of the day helped eliminate the nausea that Gleevec is notorious for.
Trey's CML Blog - Stopping - The Odds - Stop Studies - Discussion Forum Cessation Study
Big PhRMA - Medicare Status - Social Security Status - Deficit/Debt
#10
Sandeep
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Posted 24 August 2016 - 07:39 AM
In india it costs roughly 1400$ for a years supply. 400mg
#11
rcase13
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Posted 24 August 2016 - 12:41 PM
In india it costs roughly 1400$ for a years supply. 400mg
Is this for a person without insurance? That is crazy. At that price it would be worth flying in every month!
10/01/2014 100% Diagnosis (WBC 278k, Blasts 6%, Spleen extended 20cm)
01/02/2015 0.06% Tasigna 600mg
04/08/2015 0.01% Tasigna 600mg
07/01/2015 0.01% Tasigna 600mg
10/05/2015 0.02% Tasigna 600mg
01/04/2016 0.01% Tasigna 600mg
04/04/2016 PCRU Tasigna 600mg
07/18/2016 PCRU Tasigna 600mg
10/12/2016 PCRU Tasigna 600mg
01/09/2017 PCRU Tasigna 600mg
04/12/2017 PCRU Tasigna 600mg
10/16/2017 PCRU Tasigna 600mg
01/15/2018 PCRU Tasigna 600mg
Cancer Sucks!
#12
gerry
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Posted 24 August 2016 - 05:10 PM
The trouble is they are comparing apples with oranges, the majority of those countries have tax payers contributing towards the National Health Scheme, which then allows the government to negotiate the price for the medicine and the government will also cover the majority of the cost of the medicine. We pay more in tax, but most of us are happy to do that. :-).
#13
chriskuo
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Posted 25 August 2016 - 03:09 AM
Almost all patients in the US are protected from the list price, but there is a patchwork of health insurance systems in the US that gives wildly varying results in the net price to the patient.
For people over 65, Medicare provides coverage, but there is still a donut hole of several thousand dollars in addition to copays that can make specialty drugs expensive. For poor people, differing state Medicaid programs provide low-cost coverage. For most working people, employers cover most of the cost of insurance. For everybody else, they are dealing with Obamacare, which can be expensive depending on level of subsidy, or find insurance privately, or go without and possibly face fines.
So very few patients are exposed to the very high drug prices directly, but the high prices build costs into the system which mostly come out of the pockets of employers and the government. The discounts between drug manufacturers and pharmacy benefit managers and insurers is extremely opaque. In any case, people without GOOD insurance end up paying very large copays.
Basically, the drug companies exploit this disintermediation in the drug supply chain to drive large returns without bankrupting large numbers of patients.
#14
Antilogical
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Posted 25 August 2016 - 02:07 PM
I will be eligible for Medicare next year, so I've been evaluating my options. That donut hole scares me.
Dx: Sudden severe anemia detected 07/2011, followed by WBC spike. CML Dx 02/2012.
Rx: 03/2012-Gleevec400. Reduced 02/2013 to Gleevec300 due to side effects (low blood counts).
Response: PCR-Und within 7 mo. on G400. Maintained MMR4-MMR4.5 on G300. PCR-Und since 02/2016.
#15
Buzzm1
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Posted 25 August 2016 - 02:13 PM
I will be eligible for Medicare next year, so I've been evaluating my options. That donut hole scares me.
Not to worry Antilogical, the donut hole is shrinking:
While In the Donut Hole, Consumers pay:
2016: 45% for brand-names and 58% for generics
2017: 40% for brand-names and 51% for generics
2018: 35% for brand-names and 44% for generics
2019: 30% for brand-names and 37% for generics
2020: 25% for brand-names and 25% for generics
For 2016, the Medicare Donut Hole is $3,310 to $4,850.
For 2017, the Medicare Donut Hole will be $3,700 to $4,950.
For the benefit of yourself and others please add your CML history into your Signature
02/2010 Gleevec 400mg
2011 Two weakly positives, PCRU, weakly positive
2012 PCRU, PCRU, PCRU, PCRU
2013 PCRU, PCRU, PCRU, weakly positive
2014 PCRU, PCRU, PCRU, PCRU (12/07 began dose reduction w/each continuing PCRU)
2015 300, 250, 200, 150
2016 100, 50/100, 100, 10/17 TFR
2017 01/17 TFR, 04/18 TFR, 07/18 TFR 0.0012, 08/29 TFR 0.001, 10/17 TFR 0.000
2018 01/16 TFR 0.0004 ... next quarterly PCR 04/17
At the earliest opportunity, and whenever possible, lower your TKI dosage; TKIs are toxic drugs and the less we take longterm the better off we are going to be ... this is especially true for older adults.
In hindsight I should have started my dosage reduction two years earlier; it might have helped minimize some of the longterm cumulative toxic effects of TKIs that I am beset with.
longterm side-effects Peripheral Artery Disease - legs (it's a bitch); continuing shoulder problems, right elbow inflammation. GFR and creatinine vastly improved after stopping Gleevec.
Cumulative Gleevec dosage estimated at 830 grams
Taking Gleevec 400mg an hour after my largest meal of the day helped eliminate the nausea that Gleevec is notorious for.
Trey's CML Blog - Stopping - The Odds - Stop Studies - Discussion Forum Cessation Study
Big PhRMA - Medicare Status - Social Security Status - Deficit/Debt
#16
Gail's
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Posted 26 August 2016 - 12:10 AM
Buzz, I've been trying to understand this donut hole. if I understand it, when I'm in the donut hole and pick up my sprycel, the cost to me is 45% of price up to $4850. Meaning I pay $4850 for that months supply. Right?
Diagnosed 1/15/15
FISH 92%
BMB 9:22 translocation
1/19/15 began 400 mg gleevec
1/22/15 bcr 37.2 IS
2/6/15 bcr 12.5 IS
3/26/15 bcr 10.3 IS
6/29/15 bcr 7.5 IS
9/24/15 bcr 0.8 IS
1/4/16 bcr 0.3 IS
Started 100 mg dasatinib, mutation analysis negative
4/20/16 bcr 0.03 IS
8/8/16 bcr 0.007 IS
12/6/16 bcr 0.002 IS
Lowered dasatinib to 70 mg
4/10/17 bcr 0.001 IS
Lowered dasatinib to 50 mg
7/5/17 bcr 0.004 IS
8/10/17 bcr 0.001. Stopped TKI in prep for September surgery.
9/10/17 bcr 0.006
10/10/17 bcr 0.088
FISH 92%
BMB 9:22 translocation
1/19/15 began 400 mg gleevec
1/22/15 bcr 37.2 IS
2/6/15 bcr 12.5 IS
3/26/15 bcr 10.3 IS
6/29/15 bcr 7.5 IS
9/24/15 bcr 0.8 IS
1/4/16 bcr 0.3 IS
Started 100 mg dasatinib, mutation analysis negative
4/20/16 bcr 0.03 IS
8/8/16 bcr 0.007 IS
12/6/16 bcr 0.002 IS
Lowered dasatinib to 70 mg
4/10/17 bcr 0.001 IS
Lowered dasatinib to 50 mg
7/5/17 bcr 0.004 IS
8/10/17 bcr 0.001. Stopped TKI in prep for September surgery.
9/10/17 bcr 0.006
10/10/17 bcr 0.088
#17
Buzzm1
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Posted 26 August 2016 - 12:41 AM
Buzz, I've been trying to understand this donut hole. if I understand it, when I'm in the donut hole and pick up my sprycel, the cost to me is 45% of price up to $4850. Meaning I pay $4850 for that months supply. Right?
Gail, no, it means that for 2016 you will pay 45% of the $1,540 donut hole (the amount between $3,310 and $4,850) which calculates to be $693, plus whatever amount your insurance doesn't pay until you reach $3,310 on your first prescription of the calendar year, plus whatever your insurance doesn't pay beyond $4,850.
I have Kaiser Senior Advantage and once I have made it through the donut hole, and reached what is termed the catastrophic phase, I only have to pay $12 per Rx from then on. Other Medicare related additional insurances require a payment of 5% of Rx cost while in the catastrophic phase which means a $600/mo. co-payment for each $12,000 monthly prescription, after the first prescription of the year.
Lucky me, having had an employer subsidized Medicare plan, now terminated, I haven't as yet experienced that large January, or first prescription refill of the year, out-of-pocket expense.
For the benefit of yourself and others please add your CML history into your Signature
02/2010 Gleevec 400mg
2011 Two weakly positives, PCRU, weakly positive
2012 PCRU, PCRU, PCRU, PCRU
2013 PCRU, PCRU, PCRU, weakly positive
2014 PCRU, PCRU, PCRU, PCRU (12/07 began dose reduction w/each continuing PCRU)
2015 300, 250, 200, 150
2016 100, 50/100, 100, 10/17 TFR
2017 01/17 TFR, 04/18 TFR, 07/18 TFR 0.0012, 08/29 TFR 0.001, 10/17 TFR 0.000
2018 01/16 TFR 0.0004 ... next quarterly PCR 04/17
At the earliest opportunity, and whenever possible, lower your TKI dosage; TKIs are toxic drugs and the less we take longterm the better off we are going to be ... this is especially true for older adults.
In hindsight I should have started my dosage reduction two years earlier; it might have helped minimize some of the longterm cumulative toxic effects of TKIs that I am beset with.
longterm side-effects Peripheral Artery Disease - legs (it's a bitch); continuing shoulder problems, right elbow inflammation. GFR and creatinine vastly improved after stopping Gleevec.
Cumulative Gleevec dosage estimated at 830 grams
Taking Gleevec 400mg an hour after my largest meal of the day helped eliminate the nausea that Gleevec is notorious for.
Trey's CML Blog - Stopping - The Odds - Stop Studies - Discussion Forum Cessation Study
Big PhRMA - Medicare Status - Social Security Status - Deficit/Debt
#18
Buzzm1
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Posted 08 October 2016 - 01:19 PM
Ponatinib/Iclusig, which very few CML patients are prescribed, is now priced at $199,000/yr.
What outrage? Ariad raises price of its leukemia drug four times so far this year https://www.statnews...ia-drug-price/
For the benefit of yourself and others please add your CML history into your Signature
02/2010 Gleevec 400mg
2011 Two weakly positives, PCRU, weakly positive
2012 PCRU, PCRU, PCRU, PCRU
2013 PCRU, PCRU, PCRU, weakly positive
2014 PCRU, PCRU, PCRU, PCRU (12/07 began dose reduction w/each continuing PCRU)
2015 300, 250, 200, 150
2016 100, 50/100, 100, 10/17 TFR
2017 01/17 TFR, 04/18 TFR, 07/18 TFR 0.0012, 08/29 TFR 0.001, 10/17 TFR 0.000
2018 01/16 TFR 0.0004 ... next quarterly PCR 04/17
At the earliest opportunity, and whenever possible, lower your TKI dosage; TKIs are toxic drugs and the less we take longterm the better off we are going to be ... this is especially true for older adults.
In hindsight I should have started my dosage reduction two years earlier; it might have helped minimize some of the longterm cumulative toxic effects of TKIs that I am beset with.
longterm side-effects Peripheral Artery Disease - legs (it's a bitch); continuing shoulder problems, right elbow inflammation. GFR and creatinine vastly improved after stopping Gleevec.
Cumulative Gleevec dosage estimated at 830 grams
Taking Gleevec 400mg an hour after my largest meal of the day helped eliminate the nausea that Gleevec is notorious for.
Trey's CML Blog - Stopping - The Odds - Stop Studies - Discussion Forum Cessation Study
Big PhRMA - Medicare Status - Social Security Status - Deficit/Debt
#19
Billie Murawski
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Posted 09 October 2016 - 07:48 PM
Buzz, I have been very fortunate with ins covering my Sprycel, but with a new year coming I get a knot in my stomache wondering if they have any surprises for me. Ron and I are both retired on a fixed income we paid all our bills off with his severence pay so we live comfortably, and for the first time in our lives we have a small savings acct. You know how it is (send all your kids to college so they can get a job at McDonalds..If they start making me pay a large co-pay I will stop taking my Sprycel. My pcr has been 0% for six years. I just plain refuse to pay for it. And I just refuse to go back to work as a pole dancer.Gravity has been my enemy and if I got on a pole once I got upside down I would probably suffocate! Take care Billie
#20
Billie Murawski
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Posted 09 October 2016 - 07:52 PM
Buzz, I have been very fortunate with ins covering my Sprycel, but with a new year coming I get a knot in my stomache wondering if they have any surprises for me. Ron and I are both retired on a fixed income we paid all our bills off with his severence pay so we live comfortably, and for the first time in our lives we have a small savings acct. You know how it is (send all your kids to college so they can get a job at McDonalds..If they start making me pay a large co-pay I will stop taking my Sprycel. My pcr has been 0% for six years. I just plain refuse to pay for it. And I just refuse to go back to work as a pole dancer.Gravity has been my enemy and if I got on a pole once I got upside down I would probably suffocate! Take care Billie
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