Posted 09 August 2016 - 06:47 PM
Two Generic Versions of Imatinib Launched -- but Will Prices Drop?
Teva Pharmaceutical Industries has announced the launch of a generic version of imatinib mesylate, which is currently manufactured by Novartis and is sold under the brand name Gleevec.
Their generic product will be sold in 100-mg and 400-mg versions and will be available for all of the indications for which the drug has been approved by the US Food and Drug Administration (FDA).
On the same day as Teva's announcement, another drug company, Apotex Corporation, also launched a generic version of imatinib. Apotex already sells a generic formulation in Canada and will now be entering the US marketplace.
The advent of marketplace competition, especially when generic versions compete with branded names, almost always signals a decrease in price.
But the question remains: how will these new generics be priced?
Read more: http://www.medscape....c=soc_tw_share
For the benefit of yourself and others please add your CML history into your Signature
02/2010 Gleevec 400mg
2011 Two weakly positives, PCRU, weakly positive
2012 PCRU, PCRU, PCRU, PCRU
2013 PCRU, PCRU, PCRU, weakly positive
2014 PCRU, PCRU, PCRU, PCRU (12/07 began dose reduction w/each continuing PCRU)
2015 300, 250, 200, 150
2016 100, 50/100, 100, 10/17 TFR
2017 01/17 TFR, 04/18 TFR, 07/18 TFR 0.0012, 08/29 TFR 0.001, 10/17 TFR 0.000
2018 01/16 TFR 0.0004 ... next quarterly PCR 04/17
At the earliest opportunity, and whenever possible, lower your TKI dosage; TKIs are toxic drugs and the less we take longterm the better off we are going to be ... this is especially true for older adults.
In hindsight I should have started my dosage reduction two years earlier; it might have helped minimize some of the longterm cumulative toxic effects of TKIs that I am beset with.
longterm side-effects Peripheral Artery Disease - legs (it's a bitch); continuing shoulder problems, right elbow inflammation. GFR and creatinine vastly improved after stopping Gleevec.
Cumulative Gleevec dosage estimated at 830 grams
Taking Gleevec 400mg an hour after my largest meal of the day helped eliminate the nausea that Gleevec is notorious for.
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