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9 Month PCR Results


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#1 JohnFromChicago

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Posted 27 July 2016 - 04:07 PM

Today I got my 9 Month PCR results back. I am very happy with the result of 0.259%. I found it pretty hilarious that back when I got my 6 Month PCR I had used my rate of log reduction (.33 log reduction in 90 days) to plot my perspective 9 and 12 Month PCR Results and the number I came up with for my 9 Month was .26 almost the exact number of my actual result. Many people on here explained to me how silly it was to try to plot such a trend and they were most certainly right. I just find it pretty funny I calculated almost the exact actual 9 month PCR number with my crazy math. However, I am now not worried about hitting MMR by 12 Months (my 12 month result would be .12% based on my rate of log reduction calculations aka crazy math). If I get .12% or lower that would be great but as long as I am trending downwards I have finnaly come to peace with the fact that I am going to be OK and I shouldn't let the numbers give me anxiety. Special thanks to PhilB, Scuba and Trey for helping me realize that.



Diagnosed Age: 28

Diagnosed Date: Oct-20-2015

0-27 Months Rx: Sprycel 100mg

Current Rx: Sprycel 50mg


0 Month PCR = 87%

3 Month PCR = 1.2%

6 Month PCR = 0.64%

9 Month PCR = 0.26%

12 Month PCR = 0.21%

15 Month PCR = 0.15%
18 Month PCR = 0.11%

21 Month PCR = 0.05%

24 Month PCR = 0.04%

27 Month PCR = 0.01%

#2 Kellyb333

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Posted 27 July 2016 - 05:19 PM

That is great news!!!

#3 Melanie

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Posted 28 July 2016 - 12:01 AM

That's great news John from Chicago and happy you're a little more at peace.
Dx - 05/2011; PCR: 15.04; Fish: 87% Slow responder due to pancytopenia. Current - Bosulif - Nov: 2012, Mar 2016 lowered to 300 mg. 07/16 back to 400 mg. Clinical trial drug, Promacta, Feb 2013, for low Platelets.
CyCR - Aug 2014, Positive for 1 chromosome Sep 2015. PCR: 12.77 in Oct, 2012 to 0.04 (MDA) in Mar, 2016. 4/2016 - 0.126 (Local lab (IS); 05/2016 - 0.195 (local); 6/2016 - 0.07 (MDA); 7/2016 - 0.03 (local) 9/13/2016 - 0.16 (MDA); 9/26/2016 - 0.31 (MDA); 11/2016 - 0.012 (local); 01/2017 - 0.24 (MDA); 04/2017 - 0.09 (MDA); Cytogenetics show der(1:7)(q10;p10)7 chromosome mutation. Repeat of Sep 2015. PCR - 6/2017- 0.035 (local); 10/2017- 0.02 (MDA)

#4 Melanie

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Posted 28 July 2016 - 12:01 AM

That's great news John from Chicago and happy you're a little more at peace.
Dx - 05/2011; PCR: 15.04; Fish: 87% Slow responder due to pancytopenia. Current - Bosulif - Nov: 2012, Mar 2016 lowered to 300 mg. 07/16 back to 400 mg. Clinical trial drug, Promacta, Feb 2013, for low Platelets.
CyCR - Aug 2014, Positive for 1 chromosome Sep 2015. PCR: 12.77 in Oct, 2012 to 0.04 (MDA) in Mar, 2016. 4/2016 - 0.126 (Local lab (IS); 05/2016 - 0.195 (local); 6/2016 - 0.07 (MDA); 7/2016 - 0.03 (local) 9/13/2016 - 0.16 (MDA); 9/26/2016 - 0.31 (MDA); 11/2016 - 0.012 (local); 01/2017 - 0.24 (MDA); 04/2017 - 0.09 (MDA); Cytogenetics show der(1:7)(q10;p10)7 chromosome mutation. Repeat of Sep 2015. PCR - 6/2017- 0.035 (local); 10/2017- 0.02 (MDA)

#5 Pin

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Posted 28 July 2016 - 04:36 AM

That is such good news, congratulations and I'm so glad you are feeling a bit better about things. People around here are excellent for that :)

Ps. That is so awesome!! Sometimes crazy maths works, (or is an amazing coincidence) haha ;)

Diagnosed 9 June 2011, Glivec 400mg June 2011-July 2017, Tasigna 600mg July 2017-present (switched due to intolerable side effects, and desire for future cessation attempt).

Commenced monthly testing when MR4.0 lost during 2012.

 

2017: <0.01, <0.01, 0.005 (200mg Glivec, Adelaide) <0.01, 0.001 (new test sensitivity)

2016: <0.01, <0.01, PCRU, 0.002 (Adelaide)

2015: <0.01, <0.01, <0.01, 0.013

2014: PCRU, <0.01, <0.01, <0.01, <0.01

2013: 0.01, 0.014, 0.016, 0.026, 0.041, <0.01, <0.01 

2012: <0.01, <0.01, 0.013, 0.032, 0.021

2011: 38.00, 12.00, 0.14


#6 r06ue1

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Posted 28 July 2016 - 11:17 AM

Good news!  You'll be hitting MMR soon I'm sure of it!


08/2015 Initial PCR: 66.392%

12/2015 PCR: 1.573%

03/2016 PCR: 0.153%

06/2016 PCR: 0.070%

09/2016 PCR: 0.052%

12/2016 PCR: 0.036%

03/2017 PCR: 0.029%

06/2017 PCR: 0.028%

09/2017 PCR: 0.025%

12/2017 PCR: 0.018%

 

 

Taking Imatinib 400 mg


#7 JohnFromChicago

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Posted 01 August 2016 - 01:02 PM

Thanks all for the kind words of encouragement!



Diagnosed Age: 28

Diagnosed Date: Oct-20-2015

0-27 Months Rx: Sprycel 100mg

Current Rx: Sprycel 50mg


0 Month PCR = 87%

3 Month PCR = 1.2%

6 Month PCR = 0.64%

9 Month PCR = 0.26%

12 Month PCR = 0.21%

15 Month PCR = 0.15%
18 Month PCR = 0.11%

21 Month PCR = 0.05%

24 Month PCR = 0.04%

27 Month PCR = 0.01%

#8 gerry

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Posted 01 August 2016 - 04:44 PM

That is such good news, congratulations and I'm so glad you are feeling a bit better about things. People around here are excellent for that :)

Ps. That is so awesome!! Sometimes crazy maths works, (or is an amazing coincidence) haha ;)

If I remember correctly you and Trey managed to get a picture of the Big Dipper when you were plotting your results Pin. :-)

#9 Pin

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Posted 01 August 2016 - 05:15 PM

Yep, I remember that too - the pinwheel galaxy I think it was called. I still remember how helpful that conversation was for me, this place (and Trey) really got me through

Diagnosed 9 June 2011, Glivec 400mg June 2011-July 2017, Tasigna 600mg July 2017-present (switched due to intolerable side effects, and desire for future cessation attempt).

Commenced monthly testing when MR4.0 lost during 2012.

 

2017: <0.01, <0.01, 0.005 (200mg Glivec, Adelaide) <0.01, 0.001 (new test sensitivity)

2016: <0.01, <0.01, PCRU, 0.002 (Adelaide)

2015: <0.01, <0.01, <0.01, 0.013

2014: PCRU, <0.01, <0.01, <0.01, <0.01

2013: 0.01, 0.014, 0.016, 0.026, 0.041, <0.01, <0.01 

2012: <0.01, <0.01, 0.013, 0.032, 0.021

2011: 38.00, 12.00, 0.14


#10 Trey

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Posted 06 August 2016 - 04:37 PM

Trey's Big Dipper Algorithm for PCR Response:

 

http://community.lls...dose-reduction/






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