Jump to content


I need ice cream.........

  • Please log in to reply
3 replies to this topic

#1 steelpony5555


    Advanced Member

  • Members
  • PipPipPip
  • 40 posts

Posted 14 July 2016 - 11:02 PM

Ok I know I'm not suppose to eat for the 3 hour period on my Tasigna....but what constitutes food??  I mean by time ice cream gets to my tonsils it is liquid,, basically milk...and if I get a milk shake then it's half way there...so maybe the milk causes some issues.  What really is food...of course my brain is saying if it is liquid form going down it's not food..........now steak and potatos...that's food lol lol lol

#2 rcase13


    Advanced Member

  • Members
  • PipPipPip
  • 523 posts
  • LocationCharlotte, NC

Posted 15 July 2016 - 10:26 AM

I drink light fluids during that time. I asked my doc and he said it would be fine. Personally I think a milk shake would be too heavy.

10/01/2014 100% Diagnosis (WBC 278k, Blasts 6%, Spleen extended 20cm)

01/02/2015 0.06% Tasigna 600mg
04/08/2015 0.01% Tasigna 600mg
07/01/2015 0.01% Tasigna 600mg
10/05/2015 0.02% Tasigna 600mg
01/04/2016 0.01% Tasigna 600mg
04/04/2016 PCRU Tasigna 600mg
07/18/2016 PCRU Tasigna 600mg
10/12/2016 PCRU Tasigna 600mg
01/09/2017 PCRU Tasigna 600mg
04/12/2017 PCRU Tasigna 600mg
10/16/2017 PCRU Tasigna 600mg
01/15/2018 PCRU Tasigna 600mg


Cancer Sucks!

#3 Trey


    Advanced Member

  • PS Beta Group
  • PipPipPip
  • 1,705 posts
  • LocationSan Antonio, Texas

Posted 15 July 2016 - 03:13 PM

The issue is not simply any food, but high fat food.  High fat food causes all TKI drugs to remain in the body longer, which causes lawyers and others to worry about the QT prolongation issue for which Tasigna has a warning imposed by the FDA:


"Nilotinib at doses of 400 mg administered under fasting conditions on once daily schedule for 3 to 8 days had no consistent effects on the QTcF interval. When nilotinib was administered after a high fat meal as a single dose of 800 mg (C max of 1669 ng/mL) or 400 mg once daily dose after a high fat meal for 3 days (day 3 C max of 1532 ng/mL), the drug produced modest, but statistically significant increases in QTcF. The time averaged QTcF change was 6.4 msec (90% CI: 2.1-11 msec) for 400 mg once daily dose for 3 days with a high fat meal, and 7.4 msec (90% CI: 3.2-12 msec) for a single 800 mg dose with a high fat meal."


(See page 20)


If I took Tasigna, I would eat at least a small amount to have something in my stomach.  In fact, I doubt I would worry about the fasting issue at all if my QT interval was shown to be normal.  Since drug makers cannot assure people would only eat low fat foods when taking Tasigna, they make all people fast during the dosing window.  Is that a reasonable restriction?  You decide.

Edited by Trey, 15 July 2016 - 03:16 PM.

#4 steelpony5555


    Advanced Member

  • Members
  • PipPipPip
  • 40 posts

Posted 15 July 2016 - 08:51 PM

Are milkshakes high in fat?????....lol lol lol....Not the answer I was looking for lol lol

1 user(s) are reading this topic

0 members, 1 guests, 0 anonymous users