I just moved to a high allergy area. My hay fever is like a bad cold now. I'm just wondering if my neutrophil count which is half what is was before CML and TKIs can handle this.
Does anyone have any experience with this?
Trey, is there anyway you could weigh in on this?
Thx
Hay Fever and TKI
Started by
jmoorhou
, Jun 19 2016 12:45 PM
8 replies to this topic
#1
jmoorhou
-
- Members
-
- 314 posts
Advanced Member
- LocationOutside of San Francisco
Posted 19 June 2016 - 12:45 PM
Diagnosed 3/2014 WBC 28 Non detectable within 3 monthsGleevec 400 mg 5/2014 one hour after dinner really improves nausea300 mg 12/15/2016200 mg and 300 mg Gleevec 2/25/2017 (after 3 years on Gleevec) For last four months taking 300 mg per day. Last CMC showed liver enzymes elevated, went to a good Naturopath and he recommended 4 Tumeric, 10,000 mg Vitamen D, and 3 milk thistle (silymarin) daily. Also use One<p>Day Detox Dandeloin tea, and Nettle Tea and a slice of ginger every day...in two months liver tests were below normal.Janis
#2
tiredblood
-
- Members
-
- 474 posts
Advanced Member
Posted 19 June 2016 - 04:02 PM
It would be your eosinophils and basophils affected by allergy. Neutrophils with infection. You could do an internet search for pollen count for your area, that may tell you what pollen counts are high if you have a pollen allergy.
#3
Antilogical
-
- Members
-
- 284 posts
Advanced Member
- LocationPittsburgh, PA
Posted 19 June 2016 - 05:33 PM
I suffer from allergies year-round, and I use Flonase and take an antihistamine for it. That's what I did before I developed CML, and I still do it. Some days are worse than others, but I just grin and bear it....
Dx: Sudden severe anemia detected 07/2011, followed by WBC spike. CML Dx 02/2012.
Rx: 03/2012-Gleevec400. Reduced 02/2013 to Gleevec300 due to side effects (low blood counts).
Response: PCR-Und within 7 mo. on G400. Maintained MMR4-MMR4.5 on G300. PCR-Und since 02/2016.
#4
jmoorhou
-
- Members
-
- 314 posts
Advanced Member
- LocationOutside of San Francisco
Posted 19 June 2016 - 08:22 PM
Thanks
Diagnosed 3/2014 WBC 28 Non detectable within 3 monthsGleevec 400 mg 5/2014 one hour after dinner really improves nausea300 mg 12/15/2016200 mg and 300 mg Gleevec 2/25/2017 (after 3 years on Gleevec) For last four months taking 300 mg per day. Last CMC showed liver enzymes elevated, went to a good Naturopath and he recommended 4 Tumeric, 10,000 mg Vitamen D, and 3 milk thistle (silymarin) daily. Also use One<p>Day Detox Dandeloin tea, and Nettle Tea and a slice of ginger every day...in two months liver tests were below normal.Janis
#5
hannibellemo
-
- Members
-
- 728 posts
Advanced Member
- LocationNorth Central Iowa
Posted 20 June 2016 - 10:34 AM
I also deal with my seasonal allergies the same way I did before, no problems.
Pat
"You can't change the direction of the wind but you can adjust your sails."
DX 12/08; Gleevec 400mg; liver toxicity; Sprycel 100mg.; CCyR 4/10; MMR 8/10; Pleural Effusion 2/12; Sprycel 50mg. Maintaining MMR; 2/15 PCRU; 8/16 drifting in and out of undetected like a wave meeting the shore. Retired 12/23/2016! 18 months of PCRU, most recent at Mayo on 7/25/17 was negative at their new sensitivity reporting of 0.003.<p>
#6
Trey
-
- PS Beta Group
-
- 1,705 posts
Advanced Member
- LocationSan Antonio, Texas
Posted 20 June 2016 - 06:59 PM
Your WBC will respond as required to meet the need even if generally low. EOS and sometimes BAS will rise to battle allergens. EOS and BAS are normally a very small percentage of total WBC and are only manufactured in significant numbers when they are needed.
http://www.thebody.c...nt/art6013.html
#7
beno
-
- Members
-
- 92 posts
Advanced Member
- LocationIowa
Posted 21 October 2016 - 07:02 PM
My allergies appear to be significantly more sensitive since I began Sprycel. I'm taking more antihistamine than I ever have in my life and still suffering more symptoms than usual. Has anyone else had similar experiences?
DX 3/30/2016 WBC 484.2 FISH 95.3
took Hydrea 3/30-4/11
taking Sprycel 100 mg since 4/5
10 day break from Sprycel for platelet count of 12 4/26-5/8
7/07/2016 1.47% (IS)
9/30/16 BMB PCR .1259 switched to new onc
12/30/16 PCR .1569
4/7/17 PCR .0904 MMR
7/14/17 PCR .0520
12/1/17 PCR .0148
#8
tiredblood
-
- Members
-
- 474 posts
Advanced Member
Posted 22 October 2016 - 09:53 AM
Go get allergy tested. Allergy immunotherapy is generally effective.
#9
Gail's
-
- Members
-
- 634 posts
Advanced Member
Posted 22 October 2016 - 04:43 PM
I have allergy symptoms too mostly sneezing and itch eyes. Started Sprycel a few months ago and probably a coincidence that these symptoms came too. My onc said this is a particularly bad year for allergens so she thinks I'm responding to increased pollens. I've never had allergies but imagine my immune system is likely challenged by the CML and it's probably having an increased response to the pollen. Claritin is a life saver!
Diagnosed 1/15/15
FISH 92%
BMB 9:22 translocation
1/19/15 began 400 mg gleevec
1/22/15 bcr 37.2 IS
2/6/15 bcr 12.5 IS
3/26/15 bcr 10.3 IS
6/29/15 bcr 7.5 IS
9/24/15 bcr 0.8 IS
1/4/16 bcr 0.3 IS
Started 100 mg dasatinib, mutation analysis negative
4/20/16 bcr 0.03 IS
8/8/16 bcr 0.007 IS
12/6/16 bcr 0.002 IS
Lowered dasatinib to 70 mg
4/10/17 bcr 0.001 IS
Lowered dasatinib to 50 mg
7/5/17 bcr 0.004 IS
8/10/17 bcr 0.001. Stopped TKI in prep for September surgery.
9/10/17 bcr 0.006
10/10/17 bcr 0.088
FISH 92%
BMB 9:22 translocation
1/19/15 began 400 mg gleevec
1/22/15 bcr 37.2 IS
2/6/15 bcr 12.5 IS
3/26/15 bcr 10.3 IS
6/29/15 bcr 7.5 IS
9/24/15 bcr 0.8 IS
1/4/16 bcr 0.3 IS
Started 100 mg dasatinib, mutation analysis negative
4/20/16 bcr 0.03 IS
8/8/16 bcr 0.007 IS
12/6/16 bcr 0.002 IS
Lowered dasatinib to 70 mg
4/10/17 bcr 0.001 IS
Lowered dasatinib to 50 mg
7/5/17 bcr 0.004 IS
8/10/17 bcr 0.001. Stopped TKI in prep for September surgery.
9/10/17 bcr 0.006
10/10/17 bcr 0.088
1 user(s) are reading this topic
0 members, 1 guests, 0 anonymous users
