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High blood pressure

Started by martap999 , May 26 2016 11:21 PM

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2 replies to this topic

#1 martap999

Advanced Member

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30 posts

Posted 26 May 2016 - 11:21 PM

Does anyone know if Tasigna causes high blood pressure?

Thanks. Marta

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#2 Buzzm1

Advanced Member

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954 posts

LocationSilicon Valley

Posted 26 May 2016 - 11:41 PM

I only know that Gleevec moderates blood pressure. As I reduced my Gleevec dosage my blood pressure began increasing.

Known Side-effects

Tasigna Nilotinib http://bit.ly/1RNVh1i

For the benefit of yourself and others please add your CML history into your Signature

02/2010 Gleevec 400mg

2011 Two weakly positives, PCRU, weakly positive

2012 PCRU, PCRU, PCRU, PCRU

2013 PCRU, PCRU, PCRU, weakly positive

2014 PCRU, PCRU, PCRU, PCRU (12/07 began dose reduction w/each continuing PCRU)

2015 300, 250, 200, 150

2016 100, 50/100, 100, 10/17 TFR

2017 01/17 TFR, 04/18 TFR, 07/18 TFR 0.0012, 08/29 TFR 0.001, 10/17 TFR 0.000

2018 01/16 TFR PCR result pending... next quarterly PCR 04/17

At the earliest opportunity, and whenever possible, lower your TKI dosage; TKIs are toxic drugs and the less we take longterm the better off we are going to be ... this is especially true for older adults.

In hindsight I should have started my dosage reduction two years earlier; it might have helped minimize some of the longterm cumulative toxic effects of TKIs that I am beset with.

longterm side-effects Peripheral Artery Disease - legs (it's a bitch); continuing shoulder problems, right elbow inflammation. GFR and creatinine vastly improved after stopping Gleevec.

Cumulative Gleevec dosage estimated at 830 grams

Taking Gleevec 400mg an hour after my largest meal of the day helped eliminate the nausea that Gleevec is notorious for.

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