Found this site very interesting, shows how Oncologists make decisions on what's best for their patient and has a lot of other interesting information that many of us never really see including rare cases.
Found this very interesting:
patients who take <90% of their dose have 0% chance of achieving undetectable transcript levels. Missing 10% of the dose is not much, it is only 3 days per month.
Never missed a dose and never plan to.
FYI, some of the information is scary so if you are prone to giving into fear, I would suggest avoiding the link.