There has been a fair amount of discussion on stopping the tki's. I have been approached by my hematologist to participate in a drug cessation study and if the pcr goes up I would start on spyrcel. I have been on Gleevec 400 mg since diagnosis in Jan 2010 and have been undetectable since 2011, I am so reluctant and scared to do it. I would feel better about participating in a drug reduction study instead. I guess I am curious about what others think. I have followed this site since diagnosis and think it is a great supportive place to be when those tougher moments arise. Today I see the hematologist for my usual 6 month follow up so I guess that is why I am here today and think the study will come up again in the appointment. Otherwise I tend to live life trying not to think to much about having cml nor let it slow me down.
I am curious about what Trey thinks of cessation vs drug dose reduction? I know Trey has been on a reduced dose for years now and has had not problems. Also, to me 40% recurrence still seems risky.... Curious how long these studies have been going on? Is this stat on studies over 2,3,4 years? Is there some place where I can do more reading on it. Thanks for any suggestions or thoughts.