Posted 25 April 2016 - 01:44 AM
Petechiae: Pinpoint red or purple spot caused by bleeding into the skin. Causes include leukemia.
Periodically, I develop several small clusters of these spots - usually on the palm-side of the hands & fingers, especially the base of the thumb. A few days ago, I awoke to maybe 100+.
Question: Has anyone noticed a correlation to the appearance of these spots to any activity, or is it completely random? Just curious....
Sounds like what my hands look like. The spots are different sizes - a few that are readily visible, and many more that are nearly microscopic. Sometimes the larger ones are actually a collection of individual small ones that blend together from a distance. They form on my palms, the webs between fingers and on the sides of the fingers. Occasionally I'll get a splinter hemorrhage under a fingernail too.
And yes, they are related to activity. For example, one time I was out hiking on an old trail with a lot of little seedlings starting to grow in the trail. Anyway, I was pulling the little seedlings up and the next day I noticed more spots than usual.
I started Gleevec in October 2012, but didn't notice them until a couple of years ago. About a year ago I reduced from 400 to 200 per day, but they haven't gone away. Although the eye bleeds I used to occasionally get have gone away since reducing to 200. My theory is that the Gleevec causes these hemorrhages and it's not the leukemia.
My platelet count over the last couple of years has been 171 to 213.
9/25/2012 p210 transcript 118.7% IS @ Dx, begin Gleevec 400mg/day
12/2012 3.59% & bone marrow biopsy - no residual myeloproliferative features but detected 1/20 metaphases containing the Philadelphia chromosome
2013 0.914%, 0.434%, 0.412%
10/2013 0.360% & bone marrow biopsy - normal male karyotype with no evidence of a clonal cytogenetic abnormaltiy
2014 0.174%, 0.088%, 0.064%
2015 0.049%, decrease to Gleevec 200mg/day, 0.035%, 0.061%, 0.028%
2016 0.041%, 0.039%, 0.025%
2017 0.029%, 0.039%, switched to generic imatinib 200mg/day, 0.070%, 0.088%