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Early BCR-ABL Reduction Predictive of Response in Newly Diagnosed CML


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#21 Marnie

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Posted 28 April 2016 - 05:52 PM

Oh no. . .Trey and PhilB, together again. . .hold on to your hats!!!

 

(Hi, PhilB. . .good to have you back)



#22 Trey

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Posted 28 April 2016 - 08:10 PM

I'm halving a moose and buffalo flashback.....



#23 PhilB

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Posted 29 April 2016 - 02:17 AM

I thought I'd drop by and see how you were all doing.  I'm still pootling along on 200mg Glivec and wishing I could retire.

Speaking of hats, Marnie, last year my employer was pushing everyone to include a picture on their outlook profile at work and as it was only a tiny little thumbnail I used the only one I had to hand...  Fast forward to this February when I had to come over to our New Jersey office for a week long workshop.  Imagine my surprise when I found they'd grabbed everyone's outlook picture to create security passes for the building.  Apparently quite a lot of people had been looking forward to meeting me!



#24 Marnie

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Posted 29 April 2016 - 09:18 AM

That's a great story!  If only my driver's license picture was as awesome as your hat picture!

 

I highly recommend retirement, though right now, I can't do much of anything, as I recover from a separated shoulder.  Trials motorcycle mishap. 

 

No moose and buffalo out here at the new house, but the deer and rabbits are decimating everything I've planted.  I haven't yet figured out how to outsmart them.  Maybe hire some swashbuckling squirrels to keep them at bay?



#25 PhilB

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Posted 29 April 2016 - 11:30 AM

The obvious solution is to stop planting veggies and eat venison and rabbit instead.  I have a very nice rabbit casserole recipe if you need one.

Really sorry to hear about your shoulder.  I had a harpist at my wedding so your niece is definitely missing a treat.



#26 Trey

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Posted 29 April 2016 - 12:31 PM

Herodotus is available.  He is seen here doing what he does:

(NOTE: It is also a good visual on the "halving" issue discussed earlier)

Attached Files


Edited by Trey, 29 April 2016 - 12:42 PM.


#27 Marnie

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Posted 29 April 2016 - 12:35 PM

Gah!  So much for hiring the squirrels.  That is disgusting! 

 

Besides, swashbucklers always wear a jerkin, sword belt, and hat with a feather.  Herodotus is obviously low class.



#28 hannibellemo

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Posted 29 April 2016 - 04:59 PM

Hi, PhilB,

 

I'll tell you all about retirement in January! I'm certainly hoping it's all Marnie is bragging about. 

 

Don't ever change your avatar!


Pat

 

"You can't change the direction of the wind but you can adjust your sails."

DX 12/08; Gleevec 400mg; liver toxicity; Sprycel 100mg.; CCyR 4/10; MMR 8/10; Pleural Effusion 2/12; Sprycel 50mg. Maintaining MMR; 2/15 PCRU; 8/16 drifting in and out of undetected like a wave meeting the shore. Retired 12/23/2016! 18 months of PCRU, most recent at Mayo on 7/25/17 was negative at their new sensitivity reporting of 0.003.<p>


#29 Marnie

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Posted 29 April 2016 - 06:18 PM

Congratulations, Pat!  That is exciting. . .You'll be amazed at how quickly January will get here.



#30 Billie Murawski

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Posted 02 May 2016 - 08:41 PM

I can't remember, what came first the buffalo or the moose.



#31 Gail's

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Posted 02 May 2016 - 11:33 PM

Hi Billie, nice to know you're still around! How are you?
Diagnosed 1/15/15
FISH 92%
BMB 9:22 translocation
1/19/15 began 400 mg gleevec
1/22/15 bcr 37.2 IS
2/6/15 bcr 12.5 IS
3/26/15 bcr 10.3 IS
6/29/15 bcr 7.5 IS
9/24/15 bcr 0.8 IS
1/4/16 bcr 0.3 IS
Started 100 mg dasatinib, mutation analysis negative
4/20/16 bcr 0.03 IS
8/8/16 bcr 0.007 IS
12/6/16 bcr 0.002 IS
Lowered dasatinib to 70 mg
4/10/17 bcr 0.001 IS
Lowered dasatinib to 50 mg
7/5/17 bcr 0.004 IS
8/10/17 bcr 0.001. Stopped TKI in prep for September surgery.
9/10/17 bcr 0.006
10/10/17 bcr 0.088




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