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Case Study: Selecting a TKI treatment - doctor's perspective


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#1 scuba

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Posted 02 April 2016 - 07:22 AM

http://www.onclive.c...mia-case-study-

 

In the article above, Dr. Cortes leads a discussion among a panel of doctors regarding a hypothetical patient presenting with CML. What do these doctors do? It's a great read.


Diagnosed 11 May 2011 (100% FiSH, 155% PCR)

with b2a2 BCR-ABL fusion transcript coding for the 210kDa BCR-ABL protein

 

Sprycel: 20 mg per day - taken at lights out with Quercetin and/or Magnesium Taurate

6-8 grams Curcumin C3 complex.

 

2015 PCR: < 0.01% (M.D. Anderson scale)

2016 PCR: < 0.01% (M.D. Anderson scale) 

March        2017 PCR:     0.01% (M.D. Anderson scale)

June          2017 PCR:     "undetected"

September 2017 PCR:     "undetected"


#2 Harper3994

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Posted 02 April 2016 - 08:31 AM

Thanks Scuba for giving us this link. So interesting and my doctor is on the panel.

#3 tiredblood

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Posted 06 April 2016 - 11:12 PM

Cool, my doc is on the panel too.



#4 r06ue1

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Posted 07 April 2016 - 08:25 AM

Strange that most of them lean towards nilotinib instead of dasatinib, I thought nilotinib had more issues with heart than dasatinib?


08/2015 Initial PCR: 66.392%

12/2015 PCR: 1.573%

03/2016 PCR: 0.153%

06/2016 PCR: 0.070%

09/2016 PCR: 0.052%

12/2016 PCR: 0.036%

03/2017 PCR: 0.029%

06/2017 PCR: 0.028%

09/2017 PCR: 0.025%

12/2017 PCR: 0.018%

 

 

Taking Imatinib 400 mg





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