I'm having a lot of nausea I noticed someone suggested this (sorry forgot to get name), does anyone know is this ok, and does it help.
Waiting an hour after dinner to take Gleevec
Started by
jmoorhou
, Mar 05 2016 11:27 PM
7 replies to this topic
#1
jmoorhou
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Posted 05 March 2016 - 11:27 PM
Diagnosed 3/2014 WBC 28 Non detectable within 3 monthsGleevec 400 mg 5/2014 one hour after dinner really improves nausea300 mg 12/15/2016200 mg and 300 mg Gleevec 2/25/2017 (after 3 years on Gleevec) For last four months taking 300 mg per day. Last CMC showed liver enzymes elevated, went to a good Naturopath and he recommended 4 Tumeric, 10,000 mg Vitamen D, and 3 milk thistle (silymarin) daily. Also use One<p>Day Detox Dandeloin tea, and Nettle Tea and a slice of ginger every day...in two months liver tests were below normal.Janis
#3
crob20
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Posted 06 March 2016 - 02:15 PM
Makes sense to me since I have a hiatal hernia. I feel like my digestion of a bigger meal is slower. In the past, I had times when I was more likely to vomit unless I waited a while.
Diagnosed 3/09 121,000 WBC. Asymptomatic
Imatinib 400 mg started
2/10 PCRU
3/16 still PCRU but side effects worse. Stopped Imatinib for a week. Tried Sprycel 2 days.
4/16 restarted Imatinib at 300 mg.
6/16 showed 1 transcript
9/16 PCRU returned
5/1/17 Imatinib 200 mg
8/17 showed "1 transcript"
10/17 PCRU returned
Imatinib 400 mg started
2/10 PCRU
3/16 still PCRU but side effects worse. Stopped Imatinib for a week. Tried Sprycel 2 days.
4/16 restarted Imatinib at 300 mg.
6/16 showed 1 transcript
9/16 PCRU returned
5/1/17 Imatinib 200 mg
8/17 showed "1 transcript"
10/17 PCRU returned
#4
r06ue1
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Posted 07 March 2016 - 07:56 AM
I typically take mine after lunch, wait about an hour, no nausea problems. If I take it with a meal than I do feel some discomfort in my stomach.
08/2015 Initial PCR: 66.392%
12/2015 PCR: 1.573%
03/2016 PCR: 0.153%
06/2016 PCR: 0.070%
09/2016 PCR: 0.052%
12/2016 PCR: 0.036%
03/2017 PCR: 0.029%
06/2017 PCR: 0.028%
09/2017 PCR: 0.025%
12/2017 PCR: 0.018%
Taking Imatinib 400 mg
#5
RayT
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Posted 07 March 2016 - 01:20 PM
I think we're all different. When I first went on Gleevec 2 years ago, I got nauseous if I waited more than 5 minutes after eating to take it. Nowadays I just pop 400mg with a half glass of water at bedtime with no nausea, even on a completely empty stomach!
#6
trailcml
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Posted 07 March 2016 - 05:23 PM
I echo that one. I just switched over from mornings to nights to see if I could alleviate some of the fatigue. I don't have any nausea (now anyway, I did the first few days but that stopped rather quickly) but I do get fatigue from Gleevec 400mg. I always take with food and about halfway through my meal.
Diagnosed Age: 45
Diagnosed Date: Feb-19-2015
Drug/dose: Imatinib 300mg (reduced from 400mg on 1/31/2017)
Drug/dose: Imatinib 200mg (reduced from 300mg on 11/15/2017)
0 Month PCR = 20%
3 Month PCR = 0.3%
6 Month PCR = 0.03%
9 Month PCR = 0.019%
12 Month PCR = 0.0095%
15 Month PCR = 0.0104%
18 Month PCR = 0.0095%
21 Month PCR = 0.0038%
4/5/2017 PCR = 0.0057%
8/23/2017 PCR = 0.0096%
12/13/2017 PCR = 0.0114%
#7
Pin
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Posted 07 March 2016 - 06:20 PM
I'm having a lot of nausea I noticed someone suggested this (sorry forgot to get name), does anyone know is this ok, and does it help.
Might have been me - I always wait at least an hour or so after dinner, but it depends on the amount of food I ate!
Sometimes I need to wait up to two hours after a big meal, if I get the timing right I don't get any nausea at all. Not sure why it works, but it works for me.
Diagnosed 9 June 2011, Glivec 400mg June 2011-July 2017, Tasigna 600mg July 2017-present (switched due to intolerable side effects, and desire for future cessation attempt).
Commenced monthly testing when MR4.0 lost during 2012.
2017: <0.01, <0.01, 0.005 (200mg Glivec, Adelaide) <0.01, 0.001 (new test sensitivity)
2016: <0.01, <0.01, PCRU, 0.002 (Adelaide)
2015: <0.01, <0.01, <0.01, 0.013
2014: PCRU, <0.01, <0.01, <0.01, <0.01
2013: 0.01, 0.014, 0.016, 0.026, 0.041, <0.01, <0.01
2012: <0.01, <0.01, 0.013, 0.032, 0.021
2011: 38.00, 12.00, 0.14
#8
jmoorhou
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Posted 07 March 2016 - 10:53 PM
Having a small glass of milk with dinner really solved it....remember "Milk of Magnesia".. 
Diagnosed 3/2014 WBC 28 Non detectable within 3 monthsGleevec 400 mg 5/2014 one hour after dinner really improves nausea300 mg 12/15/2016200 mg and 300 mg Gleevec 2/25/2017 (after 3 years on Gleevec) For last four months taking 300 mg per day. Last CMC showed liver enzymes elevated, went to a good Naturopath and he recommended 4 Tumeric, 10,000 mg Vitamen D, and 3 milk thistle (silymarin) daily. Also use One<p>Day Detox Dandeloin tea, and Nettle Tea and a slice of ginger every day...in two months liver tests were below normal.Janis
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