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Perhaps some good news coming tomorrow
Started by
Mr.Tee
, Dec 04 2015 03:10 PM
11 replies to this topic
#2
sunshineC
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Posted 04 December 2015 - 04:01 PM
Hey Mr. Tee!
So..... (me being not as smart as the average bear) you're saying the results of that Phase I trial we were talking about before is coming out tomorrow? And are they talking about a whole med TKI for people like us who lost results with Sprycel and had to switch to Tasigna? Or people who don't get results from Sprycel or Tasigna? Sorry, I feel so stupid about all this, but it is who I am. I would rather ask the stupid questions and gain some information than not bother asking.
Also, have you started your Tasigna yet? Could you please look at the new post I just put up and respond?
Thanks,
#3
Trey
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Posted 04 December 2015 - 08:14 PM
I also wrote about the ABL001 drug 6 months ago. Good to see some data is due out soon.
http://community.lls...ects/?hl=abl001
https://trialbulleti...try/ct-02081378
Edited by Trey, 04 December 2015 - 08:16 PM.
#4
Cool Hand Leuk
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#5
kat73
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Posted 07 December 2015 - 10:39 AM
Golly, this would be so great if it pans out, since what Trey said about it was the most encouraging news I've heard in awhile - it fits in the lock in a different/tighter place and doesn't hit all those other places that give us the side effects. Even if it didn't deliver any degree of stem cell killing property, it would be preferable to be on for the long haul. If it could solve the fatigue, wow, wouldn't that be great? (And, personally, I would REALLY like to return to my own eyes of old, and get rid of these Trump-like toad puffy lids.)
Dx July 2009 on routine physical. WBC 94. Started Gleevec 400 mg Sept 2009. MMR at 2yrs. Side effects (malaise, depression/anxiety, fatigue, nausea, periorbital edema) never improved. Kidney issues developed because of Gleevec. Switched to Sprycel 70 mg in Aug 2011. Above side effects disappeared or improved. Have been MR3.5 - 4.5 ever since. Two untreated pleural effusions followed by one treated by stopping Sprycel Jan 2017. After 9 weeks, PCR showed loss of MMR; re-started Sprycel at 50 mg and in 3 months was back to <0.01% IS. Pleural effusion returned within a couple of months, same as before (moderate, left side only). Stopped Sprycel 50 mg for 12 weeks; pleural effusion resolved. At about a monthoff the drug, PCR was 0.03; at 11 weeks it was 2.06 - lost CCyR? Have returned to 50 mg Sprycel for 3 weeks, intending to reduce to 20 mg going forward.
#7
DebDoodah22
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Posted 21 December 2015 - 10:10 AM
I'm with you Kat73
#8
r06ue1
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Posted 22 December 2015 - 04:04 PM
Sounds very promising, looking forward to completion of Human trials. 
08/2015 Initial PCR: 66.392%
12/2015 PCR: 1.573%
03/2016 PCR: 0.153%
06/2016 PCR: 0.070%
09/2016 PCR: 0.052%
12/2016 PCR: 0.036%
03/2017 PCR: 0.029%
06/2017 PCR: 0.028%
09/2017 PCR: 0.025%
12/2017 PCR: 0.018%
Taking Imatinib 400 mg
#10
JPD
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Posted 07 May 2016 - 10:58 AM
we all just gotta hold on for another 5 - 10 years. We'll see a "cure".
January 15: .53%
April 15: .78%
July 15: 1.1% - upped dosage to 400mg after this test
Oct 15: .85%
December 15: .28%
March 16: .29%
July 16: .34%
October 16: .11%
January 17: .081%
April 17: .055%
July 17: .135%
Oct 17: .008%
#11
r06ue1
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Posted 09 May 2016 - 05:57 AM
I just want this new medicine released already, sounds a lot better than any of the current medications available. I wonder how long it could take to see it on the market?
08/2015 Initial PCR: 66.392%
12/2015 PCR: 1.573%
03/2016 PCR: 0.153%
06/2016 PCR: 0.070%
09/2016 PCR: 0.052%
12/2016 PCR: 0.036%
03/2017 PCR: 0.029%
06/2017 PCR: 0.028%
09/2017 PCR: 0.025%
12/2017 PCR: 0.018%
Taking Imatinib 400 mg
#12
rcase13
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Posted 09 May 2016 - 10:01 AM
It seems like if you meet the requirements you would also be searching for a BMT match as well.
10/01/2014 100% Diagnosis (WBC 278k, Blasts 6%, Spleen extended 20cm)
01/02/2015 0.06% Tasigna 600mg
04/08/2015 0.01% Tasigna 600mg
07/01/2015 0.01% Tasigna 600mg
10/05/2015 0.02% Tasigna 600mg
01/04/2016 0.01% Tasigna 600mg
04/04/2016 PCRU Tasigna 600mg
07/18/2016 PCRU Tasigna 600mg
10/12/2016 PCRU Tasigna 600mg
01/09/2017 PCRU Tasigna 600mg
04/12/2017 PCRU Tasigna 600mg
10/16/2017 PCRU Tasigna 600mg
01/15/2018 PCRU Tasigna 600mg
Cancer Sucks!
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