First Fish BCR/ABR results
Posted 05 November 2015 - 02:59 PM
I've just received my first Fish report after dx 3 months ago, and it reads:
'result is within normal limits (<1% of nuclei with BCR/ABL fusion).
Please what does this mean?
Posted 05 November 2015 - 05:14 PM
Posted 05 November 2015 - 05:36 PM
Fish is negative. That is Complete Cytogenetic Response (CCyR). Equivalent roughly to a 2 log reduction in PCR. Next goal is Major Molecular response (MMR) which is a 3 log reduction in PCR or .1% PCR.
Very good for only 3 months. Congratulations.
Posted 06 November 2015 - 12:16 PM
In addition to my Fish report, I have received the following:
BCR-ABL Rearrangement PCR, Blood:- Positive, 0.04
Kindly please tell me what it means.
Posted 06 November 2015 - 07:10 PM
Is this .04% ? It must be a percentage to be useful. If it is not clear, ask your Onc.
If it is a percentage, it would be MMR (3 log reduction) since you are better than .1% (also assuming your PCR uses International Standard). So if the number is a percentage, and it is also International Standard, it is better than MMR.
Posted 06 November 2015 - 08:53 PM
Posted 06 November 2015 - 09:38 PM
MMR means Major Molecular response (MMR) which is a 3 log reduction in PCR or .1% PCR.
Achieving this in only 3 months is a very fast response. Outstanding.
Posted 01 December 2015 - 01:29 PM
I had another test, I guess PCR, and the results read:
the expression level of BCR-ABL transcripts is equivalent to international standard 0.01% BCR-ABL ratio. This is most consistent with an extremely low level positive result.
Please what does this mean? I had similar test about 3 weeks before this and it was 0.04%. I have so far been dx 4 months and on 100mg spyrcel.
Posted 01 December 2015 - 10:32 PM
I think you are reading the standard information provided on the PCR test results sheet, and it does not mean your result was .1%. As you said, your result was .04%, which is better than .1%.
Again, you are doing much better than average.
Posted 01 December 2015 - 11:17 PM
Posted 02 December 2015 - 09:27 AM
Unless you provide an exact quote it is impossible for us to tell you what it means.
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