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TKIs Result in Excellent Clinical Outcomes in Chronic Phase CML

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#1 mdszj


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Posted 23 October 2015 - 04:44 PM


dx cml 7/2012; 100 mg sprycel; splenectomy 9/2012; reached prcu 10/2013; dx smoldering myeloma 1/2015; 80 mg sprycel 12/2015; 50 mg sprycel 7/13/16; discontinued sprycel 11/15/16

#2 snowbear


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Posted 23 October 2015 - 06:31 PM

1,140 deaths per year FROM CML seems high.  :(

#3 Tedsey


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Posted 24 October 2015 - 08:09 PM

Yes.  It does.  In my opinion, the American CC is the worst place to go to get info when dx (very gloom and doom and lotsa talk about death).  It is weird that an article that talks about CP CML would put in such a ubiquitous quote at the end--it doesn't equate. 


Boo! to the author who does not understand what he is writing about!  Anyway, the annual death rate quoted is likely due to those dx in AP or BP and the minority of folks dx in CP that progress despite treatment.


Grumble, grumble...

#4 soundoff


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Posted 25 October 2015 - 12:12 AM

Agreed! The death numbers are not correct.

#5 Trey


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Posted 25 October 2015 - 09:51 AM

The stats they use came from averaging many years of data, back to before TKI drugs.  Using stats that way when there has been a course altering change like TKI drugs is poor statistical practice, to say the least.

#6 R0f03l


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Posted 25 October 2015 - 01:30 PM

This number of deaths should not be only the disease more also caused by its effects.

#7 chrissy778


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Posted 23 November 2015 - 08:00 AM

Thank you Trey.. I always find myself reading even when I know I should turn away.. Then after I read it I feel like Whyyy? did I do that to myself.. Thank you for explaining how they got their numbers....

Its never to late to live happily ever after/ Do not squander time; for that's the stuff life is made of

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