It took me about 6-8 months to experience the full effects of Gleevec. At that time most of us were on it so we had some very interesting and funny conversations.
I moved on to Sprycel because of liver issues with Gleevec and I had a very difficult 4-6 month breaking in period. After that it has, mostly, been a breeze. I did develop a pleural effusion 2.5 years in, but dose reduction seems to have solved that.
Only you can answer your own question, but you have to temper it with the idea that none of these drugs are going to work for us if we don't give them a chance. I think docs tell us "all you have to do is take a pill" and many of them really believe it so we are shocked when it just simply isn't that easy.
There are side effects with all of these drugs, but, from what I have read, none of the side effects hold a candle to dying from this disease. So you have to decide what you will tolerate and try to figure it out with the help of your doc.
"You can't change the direction of the wind but you can adjust your sails."
DX 12/08; Gleevec 400mg; liver toxicity; Sprycel 100mg.; CCyR 4/10; MMR 8/10; Pleural Effusion 2/12; Sprycel 50mg. Maintaining MMR; 2/15 PCRU; 8/16 drifting in and out of undetected like a wave meeting the shore. Retired 12/23/2016! 18 months of PCRU, most recent at Mayo on 7/25/17 was negative at their new sensitivity reporting of 0.003.<p>