Jump to content


Photo

Bosulif~ new medication


  • Please log in to reply
2 replies to this topic

#1 JBow82

JBow82

    Member

  • Members
  • PipPip
  • 10 posts
  • LocationSouthern, NJ

Posted 26 August 2015 - 06:40 PM

Any info or feedback about this drug?

#2 SusanL

SusanL

    Advanced Member

  • Members
  • PipPipPip
  • 44 posts

Posted 27 August 2015 - 01:52 PM

there is a post Aug 14, 2015. " Bosulif, anyone taking?"  Quite a few shared their experiences with it.



#3 Buzzm1

Buzzm1

    Advanced Member

  • Members
  • PipPipPip
  • 972 posts
  • LocationSilicon Valley

Posted 27 August 2015 - 02:24 PM

Any info or feedback about this drug?

 

there is a post Aug 14, 2015. " Bosulif, anyone taking?"  Quite a few shared their experiences with it.

 

the link to it: http://community.lls...yone-taking-it/


For the benefit of yourself and others please add your CML history into your Signature

 

02/2010 Gleevec 400mg

2011 Two weakly positives, PCRU, weakly positive

2012 PCRU, PCRU, PCRU, PCRU

2013 PCRU, PCRU, PCRU, weakly positive

2014 PCRU, PCRU, PCRU, PCRU (12/07 began dose reduction w/each continuing PCRU)

2015 300, 250, 200, 150

2016 100, 50/100, 100, 10/17 TFR

2017 01/17 TFR, 04/18 TFR, 07/18 TFR 0.0012, 08/29 TFR 0.001, 10/17 TFR 0.000

2018 01/16 TFR 0.0004 ... next quarterly PCR 04/17

 

At the earliest opportunity, and whenever possible, lower your TKI dosage; TKIs are toxic drugs and the less we take longterm the better off we are going to be ... this is especially true for older adults.  

 

In hindsight I should have started my dosage reduction two years earlier; it might have helped minimize some of the longterm cumulative toxic effects of TKIs that I am beset with.  

 

longterm side-effects Peripheral Artery Disease - legs (it's a bitch); continuing shoulder problems, right elbow inflammation.   GFR and creatinine vastly improved after stopping Gleevec.

 

Cumulative Gleevec dosage estimated at 830 grams

 

Taking Gleevec 400mg an hour after my largest meal of the day helped eliminate the nausea that Gleevec is notorious for.  

 

Trey's CML BlogStopping - The OddsStop Studies - Discussion Forum Cessation Study

Big PhRMA - Medicare Status - Social Security Status - Deficit/Debt





1 user(s) are reading this topic

0 members, 1 guests, 0 anonymous users