Jump to content


Fluctuating PCR

  • Please log in to reply
1 reply to this topic

#1 elvis


    Advanced Member

  • Members
  • PipPipPip
  • 37 posts

Posted 05 June 2015 - 07:31 PM

Hi All,


I am sprycel 100mg for the last 15 months and Tasigna for last 4.5 years and a year on Gleevec before that.  Dxed in 2009.


My PCR has been fluctuating on Sprycel 100 mg.


When starting sprycel I had 3 log reduction from Tasigna but was plateauing so was switched to Sprycel.


On international scale my PCR was 0.100


After 2 months of sprycel it came down to 0.05

After 4 months  of sprycel it came down to 0.035

For next 3 pcrs in about it climbed upto 0.090

Last 2 PCRs it was about 0.040


Latest PCR today it went about 0.06.


Little confused with the jump around. My doctor is cautious and little watchful but not worried.


Any thoughts or guidance?  Anyone has seen this seesaw pattern.




#2 Trey


    Advanced Member

  • PS Beta Group
  • PipPipPip
  • 1,705 posts
  • LocationSan Antonio, Texas

Posted 05 June 2015 - 08:05 PM

You have remained at more than 3 log reduction for 15 months.  No problem.  Just an extended plateau which will turn down at some point.

1 user(s) are reading this topic

0 members, 1 guests, 0 anonymous users