I am sprycel 100mg for the last 15 months and Tasigna for last 4.5 years and a year on Gleevec before that. Dxed in 2009.
My PCR has been fluctuating on Sprycel 100 mg.
When starting sprycel I had 3 log reduction from Tasigna but was plateauing so was switched to Sprycel.
On international scale my PCR was 0.100
After 2 months of sprycel it came down to 0.05
After 4 months of sprycel it came down to 0.035
For next 3 pcrs in about it climbed upto 0.090
Last 2 PCRs it was about 0.040
Latest PCR today it went about 0.06.
Little confused with the jump around. My doctor is cautious and little watchful but not worried.
Any thoughts or guidance? Anyone has seen this seesaw pattern.