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Fertility and Tasigna

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#1 kavis



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Posted 25 April 2015 - 04:14 PM

Hello - I'm 3 months into Tasigna and CML.  I'm single with no kids, but would like to have them someday.  Anyone have any experience?  I've had one doc tell me to go off it for 2 months, another doc tell me I have nothing to worry about (emphasizing they are concerned with females carrying more than males).



Male, Dx Jan '15 in Chronic Phase at age 35

Tasigna 600mg


PCR highlights:

1/10/15 - 74.8%

April '15 - 1.7%

Oct '15 - 0.48%

Mar '16 - 0.24%

Apr '16 - 0.08%

July '16 - 0.09%

Oct '16 - 0.06%

Jan '17 - 0.0684%

April '17 - 0.08233%

July '17 - 0.034407%

Oct '17 - 0.043

Jan '18 - 0.028


#2 Frogiegirl


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Posted 26 April 2015 - 10:45 AM

I get your concerns! I'm not sure if it's the same for males. ...but a two month med break would probably feel great! I have two little boys and I'm wanting one more. ..my doc is trying to get my numbers bottomed out and then we're talking preggers. Since it's the development and the baby being exposed to the tki I'm sure it's a bit different for males. ....lucky ducks:)

Diagnosed Oct 2013 Started 600mg of Tasigna  on Nov 4th. Lowered dose a few months later to 300mg due to side affects stayed here declining PCR until March 2015 small jump from 0.0072 to 0.0083 scarred my doc into full dose of Tasigna again 600mg(been miserable since) but reached PCRU 06/15/2015(next test) and have been there ever since. Hoping to have another little one. I have the support of my doc to go off anytime, just scared to jump. might go two years PCRU but he said it wont make much of a difference. I just figured I could possibly go into a trial while preggers if I got the two years behind me.

Nov 8th 2017 went off Tasigna

Dec 1st PCRU off TKI

Jan 5th PCR Detected .0625

Feb 1st PCR Detected .7815

Added 8-6 grams Curcumin daily in Feb

March 3rd PCR Detected 3.2646 YIKES!

 stopped trying for baby after February reading. will start new TKI march 16th 2017 (Sprycel)

FYI I'm not done trying for my last little one.

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