Question about my 3-month Gleevec dosage reduction experiment (I'm approaching month 1). Since I have plenty of Gleevec 400mg tablets, the doc suggested that I score the existing tablets to get 200mg/daily. He didn't seem concerned with the accuracy issues inherent in scoring (e.g., I guess it could be off by a few mg?), but I wanted to see if others have scored Gleevec for an extended period (> 1 month) and was everything okay?
Since this is a short-term experiment and probably due to cost issues, we did not change my prescription or switch to 100mg tablets. I've just been using a pill splitter to score what I have.
What's the risk in scoring Gleevec 400mg tablets for a 200mg dosing schedule (using a pill splitter)?