hey everybody, do you know what kind of food that can interact badly (like decrease the effectiveness) with tasigna? do you know if kiwi, passion fruit, pineapple and guava have some interaction? thanks in advance. happy easter to everybody!!
tasigna and food interaction
Started by
Lucas
, Apr 03 2015 04:49 PM
28 replies to this topic
#2
Antilogical
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Posted 03 April 2015 - 04:55 PM
Contraindications with food are usually on the drug websites.
Dx: Sudden severe anemia detected 07/2011, followed by WBC spike. CML Dx 02/2012.
Rx: 03/2012-Gleevec400. Reduced 02/2013 to Gleevec300 due to side effects (low blood counts).
Response: PCR-Und within 7 mo. on G400. Maintained MMR4-MMR4.5 on G300. PCR-Und since 02/2016.
#3
JPD
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Posted 03 April 2015 - 06:02 PM
only thing Ive ever been told is grapefruit/grapefruit juice
January 15: .53%
April 15: .78%
July 15: 1.1% - upped dosage to 400mg after this test
Oct 15: .85%
December 15: .28%
March 16: .29%
July 16: .34%
October 16: .11%
January 17: .081%
April 17: .055%
July 17: .135%
Oct 17: .008%
#4
Frogiegirl
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Posted 03 April 2015 - 06:30 PM
Yep I'm with JPD only was told to stay away from grapefruit.....I'm an extremist I even check my bath and lotion products for grapefruit extract. .....over board I know:)
Diagnosed Oct 2013 Started 600mg of Tasigna on Nov 4th. Lowered dose a few months later to 300mg due to side affects stayed here declining PCR until March 2015 small jump from 0.0072 to 0.0083 scarred my doc into full dose of Tasigna again 600mg(been miserable since) but reached PCRU 06/15/2015(next test) and have been there ever since. Hoping to have another little one. I have the support of my doc to go off anytime, just scared to jump. might go two years PCRU but he said it wont make much of a difference. I just figured I could possibly go into a trial while preggers if I got the two years behind me.
Nov 8th 2017 went off Tasigna
Dec 1st PCRU off TKI
Jan 5th PCR Detected .0625
Feb 1st PCR Detected .7815
Added 8-6 grams Curcumin daily in Feb
March 3rd PCR Detected 3.2646 YIKES!
stopped trying for baby after February reading. will start new TKI march 16th 2017 (Sprycel)
FYI I'm not done trying for my last little one.
#5
Trey
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Posted 03 April 2015 - 07:23 PM
The main thing I would avoid is calcium pills along with the TKI drug. Otherwise I would eat any food (not applying this to herbals).
I eat Texas Ruby Red grapefruit whenever it is in season. Yum, yum. If I could find Texas Ruby Red grapefruit body wash I would use it. If I did enemas I would......well, no need to get carried away.....
#6
Billie Murawski
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Posted 03 April 2015 - 10:58 PM
You can't help yourself, you're a FROG 
#7
Billie Murawski
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Posted 03 April 2015 - 11:12 PM
Trey, Have you looked at bath and bodyworks, They have every scent possible. I'll look next time I go up there. If they have grapefruit scents you'll probably fall in love with yourself and not talk to us anymore.
Because of my vascular disease my surgeon told me I can't take anything with calcium at all. So there's another thing we can't take without talking with our doctors.
#8
Billie Murawski
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Posted 03 April 2015 - 11:15 PM
The main thing I would avoid is calcium pills along with the TKI drug. Otherwise I would eat any food (not applying this to herbals).
I eat Texas Ruby Red grapefruit whenever it is in season. Yum, yum. If I could find Texas Ruby Red grapefruit body wash I would use it. If I did enemas I would......well, no need to get carried away.....
I done had me a ruby red grapefruit enema. Sounds like a county western song.
#9
Gail's
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Posted 04 April 2015 - 03:23 PM
Billie, it's only a country song if you were giving yourself the grapefruit enema while your girlfriend stole your truck, ran over your dog, and shot a bad guy.
Diagnosed 1/15/15
FISH 92%
BMB 9:22 translocation
1/19/15 began 400 mg gleevec
1/22/15 bcr 37.2 IS
2/6/15 bcr 12.5 IS
3/26/15 bcr 10.3 IS
6/29/15 bcr 7.5 IS
9/24/15 bcr 0.8 IS
1/4/16 bcr 0.3 IS
Started 100 mg dasatinib, mutation analysis negative
4/20/16 bcr 0.03 IS
8/8/16 bcr 0.007 IS
12/6/16 bcr 0.002 IS
Lowered dasatinib to 70 mg
4/10/17 bcr 0.001 IS
Lowered dasatinib to 50 mg
7/5/17 bcr 0.004 IS
8/10/17 bcr 0.001. Stopped TKI in prep for September surgery.
9/10/17 bcr 0.006
10/10/17 bcr 0.088
FISH 92%
BMB 9:22 translocation
1/19/15 began 400 mg gleevec
1/22/15 bcr 37.2 IS
2/6/15 bcr 12.5 IS
3/26/15 bcr 10.3 IS
6/29/15 bcr 7.5 IS
9/24/15 bcr 0.8 IS
1/4/16 bcr 0.3 IS
Started 100 mg dasatinib, mutation analysis negative
4/20/16 bcr 0.03 IS
8/8/16 bcr 0.007 IS
12/6/16 bcr 0.002 IS
Lowered dasatinib to 70 mg
4/10/17 bcr 0.001 IS
Lowered dasatinib to 50 mg
7/5/17 bcr 0.004 IS
8/10/17 bcr 0.001. Stopped TKI in prep for September surgery.
9/10/17 bcr 0.006
10/10/17 bcr 0.088
#10
winespritzer
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Posted 04 April 2015 - 07:01 PM
Trey,
My doctor told me not to take Algae Cal supplements within 2 hrs of taking Sprycel. Would that include not having lasagna or drinking calcium enriched soymilk at dinner? BMS didn't know the answer and I haven't remembered to ask the onc. Figured you probably know.
Wines[rizer
CML History....
DX-1/14....wbc....55....100mg Sprycel-1 wk after DX....periorbital edema, fatigue,
.385-4/14
.365-7/14
.13-10/14
.11-1/15
.045-4/15
.07-7/15
.06-10/15
.04-1/16
0.00- 4/16-10/17
70mg Sprycel...11/4/17....40 mg prednisone (7 days)....thoracentisis...10/26/17
tremendous reduction w periorbital edema and fatigue
#11
Billie Murawski
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Posted 04 April 2015 - 10:05 PM
That's a good one Gail, what a predicament. Instead of a country western song we should write a Gleevac Sharts song, Every time I got them all hell would break loose phones,people knocking at the door (who always want to save us) they better stay away and save themselves.,oven timer goes off etc. I bet everybody on the board has some very interesting stories.
In Florida we saw a girl walking down the street wearing a garbage bag not a bad idea for those taking a tki especially Gleevac., if we had an accident all we would have to do is find a hose rinse ourselves off hose off the garbage bag turn it inside out and put it back on.!
#12
Lucas
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Posted 05 April 2015 - 06:30 AM
thansk, guys. trey, when you talk about calcium you talk about only calcium pills or any supplement with calcium? cheers and a happy easter!!
#13
winespritzer
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Posted 05 April 2015 - 09:35 AM
Hi Lucas,
Happy to see your writings. Hope all is well and the numbers are dropping. Hoping/dreaming we can quit the tki's someday.
Ginger
Winespritzer
CML History....
DX-1/14....wbc....55....100mg Sprycel-1 wk after DX....periorbital edema, fatigue,
.385-4/14
.365-7/14
.13-10/14
.11-1/15
.045-4/15
.07-7/15
.06-10/15
.04-1/16
0.00- 4/16-10/17
70mg Sprycel...11/4/17....40 mg prednisone (7 days)....thoracentisis...10/26/17
tremendous reduction w periorbital edema and fatigue
#14
Lucas
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Posted 05 April 2015 - 10:11 AM
Thanjs, Ginge/winespritzer! My numbers were dropping the last time. I'll have a PCR teste tomorrow, só fingers crossed and hope the trend continues to Góes down and down!
#15
Lucas
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Posted 05 April 2015 - 10:11 AM
Hope yiu're Alright too!!
#16
Trey
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Posted 05 April 2015 - 03:28 PM
Only the big calcium pills. That would include AlgeaCal (which is a calcium pill). I don't take calcium pills. I eat lots of cheese to get minerals since it is absorbed far better. As I said, I don't worry about any foods rich in calcium along with TKIs. The issue is not TKI specific, it is most pills where absorption is an important issue.
#18
winespritzer
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Posted 05 April 2015 - 06:29 PM
Dear Trey and Marnie,
Thanks much. I will resume my soy milk and Hagen Daz ice cream bars. . . maybe even the baby goudas I love to nibble on. And I get the part about the absorption. I have osteo so must take calcium supplements.
So grateful for this forum.
Winespritzer
CML History....
DX-1/14....wbc....55....100mg Sprycel-1 wk after DX....periorbital edema, fatigue,
.385-4/14
.365-7/14
.13-10/14
.11-1/15
.045-4/15
.07-7/15
.06-10/15
.04-1/16
0.00- 4/16-10/17
70mg Sprycel...11/4/17....40 mg prednisone (7 days)....thoracentisis...10/26/17
tremendous reduction w periorbital edema and fatigue
#19
winespritzer
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Posted 05 April 2015 - 06:31 PM
Hi Lucas,
Will keep you in my thoughts tomorrow that the numbers keep going down below down.
Ginger/
Winespritzer
CML History....
DX-1/14....wbc....55....100mg Sprycel-1 wk after DX....periorbital edema, fatigue,
.385-4/14
.365-7/14
.13-10/14
.11-1/15
.045-4/15
.07-7/15
.06-10/15
.04-1/16
0.00- 4/16-10/17
70mg Sprycel...11/4/17....40 mg prednisone (7 days)....thoracentisis...10/26/17
tremendous reduction w periorbital edema and fatigue
#20
Marnie
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Posted 05 April 2015 - 07:30 PM
Baby gouda. . .mmmmm.
Jarlsburg. . .mmmmm
Dubliner. . .mmmmmm
Havarti with dill. . .mmmmm
I love cheese. It's amazing I haven't died of a heart attack. Fortunately, I have fabulous cholesterol numbers. . .my doc said they are the best she's ever seen.
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