I was diagnosed with CML in November 2014. At that time, an MRI that I had done showed lytic lesions on my spine (and a few others scattered in other parts of my body). My oncologist was concerned with this and eventually sent me to MD Anderson in Houston. Since that MRI was done, I started on Tasigna and am doing very well (blood counts almost normal; bmb at 1% blast). My doctor at MD Anderson decided to wait to have me do another MRI (after I have been on the Tasigna for 3 months). He said that what "generally" happens is that the lesions shrink/disappear b/c of taking the Tasigna. (If they don't, he mentioned chemo, which scares the you-know-what out of me). Has anybody else had lesions (painless) show in the spinal area? If so, did they, indeed shrink/disappear after taking a TKI? Any help would be appreciated. (I'm freaked out by this!) Thanks.