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Gleevec / Cymbalta

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#1 snowbear


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Posted 16 January 2015 - 12:15 PM

Has anybody been able to take both Gleevec and Cymbalta without it putting you in a coma or making you feel like a zombie?


Before my docs even *suspected* leukemia, I was prescribed Cymbalta for chronic pain.  At the time they thought I had lupus and possibly fibromyalgia.  No matter what the cause, it has worked wonders.  I felt better, have less pain, and even though I didn't think I was depressed, my energy levels and mood improved. 


After the first 30 days at 30 mg, doc increased the dose to 60 mg.  It was shortly afterwards that I got the CML diagnosis and because my Hema/Onc was concerned about an interaction between these two medications, she lowered the Cymbalta back down to 30 mg.  A few weeks later after she discussed it with a pharmacist, she said it was okay for me to go back up to 60 mg since I got better pain relief at the higher dose.  I told doc this week that I just can't stay awake and she wants me to go back down to 30 mg.  This is 5 adjustments in less than two months!!! 


So not only am in la-la land most of the time, I'm going crazy!  I feel like crying at the drop of a pin and am dwelling on a somewhat recent break-up that I was sure I was over.  I can't stand feeling like this.  I skipped both meds for the past 2 days hoping it would clear my system and clear my head, but it just seems to be making things worse and I know I can't play around with either of these medications.  Skipping doses of Gleevec could kill me but the Cymbalta is going to put me in the nuthouse.

#2 Billie Murawski

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Posted 16 January 2015 - 03:18 PM

Hi Snowbear,

 When I was first dx I was put on 400mg Gleevac, 3 weeks later I was put on 60mg cymbalta, I have been on the cymbalta ever since. I have had no problems with it even when I was on 100mg Sprycel and it definitely helps my joint pain.                  Billie

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