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For me, the price of Gleevec went up again


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#1 Widgeonus

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Posted 12 January 2015 - 08:00 AM

$13,942 for 30 days of 600mg. Went up $900 in a month. How is this even remotely possible.

 

Thankfully I have good insurance and the co-pay remains the same, but this is the 3rd time it's went up in a year.

 

Off my soap box.

 

Have a good day.



#2 Floa7

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Posted 12 January 2015 - 08:25 AM

$28050 for a 90 day supply of Gleevec 400mg. The doc just increased mine to 600 mg. The doc said 100 mg cost the same as a 400mg. and your not suppose to break a 400mg into.

I have a cap of $400k on my insurance. I go on Medicare in October, Well I am running out of insurance before Oct. providing I don't get sick and can't afford to increase the gleevec. I also have a good co-pay.

 

What do I do?

Lot of prayers


1 2012 CML detected Started Gleevec 400 mg

In nov 2014 my pcr started to rise by Feb I stopped Gleevec and went onto

2 2015 Tasigna 600 mg/day

I have been PCRU for 2 years and stopped Tasigna 4 7 2017

5 8 2017 results 0.008

5 30 2017 results 0.028 

6 30 2017 results 0.3, I have restarted the Tasigna because it went above 0.1 

 

My son

11 2011 CML detected Started Gleevec 400 mg

He went 2 1/2 years on gleevec and lost PCRU

Started Sprycel went PCRU for 2 years and stopped the Sprycel, went back for 3 month checkup and PCR was 8.0

He went back onto Sprycel and now is PCRU again

3 16 2017 results 0.008

6 1 2017 results 0.002


#3 rcase13

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Posted 12 January 2015 - 09:13 AM

The one thing the ACA did do right is ban annual limits and lifetime limits. Your plan might be grandfathered in. If so time to get a new plan! You won't have to worry about that on a new plan.

10/01/2014 100% Diagnosis (WBC 278k, Blasts 6%, Spleen extended 20cm)

01/02/2015 0.06% Tasigna 600mg
04/08/2015 0.01% Tasigna 600mg
07/01/2015 0.01% Tasigna 600mg
10/05/2015 0.02% Tasigna 600mg
01/04/2016 0.01% Tasigna 600mg
04/04/2016 PCRU Tasigna 600mg
07/18/2016 PCRU Tasigna 600mg
10/12/2016 PCRU Tasigna 600mg
01/09/2017 PCRU Tasigna 600mg
04/12/2017 PCRU Tasigna 600mg
10/16/2017 PCRU Tasigna 600mg
01/15/2018 PCRU Tasigna 600mg

 

Cancer Sucks!


#4 Buzzm1

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Posted 12 January 2015 - 11:32 AM

Gleevec has been increasing in price, twice a year, ever since I first priced it at $3900 for 30 days 400mg in late October. 2009

Last time I checked, it was priced at $8983 for 30 days 400mg; $299.43/400mg pill

The price has obviously been increased yet again since.

Gleevec goes generic in the U.S. in February, 2016


For the benefit of yourself and others please add your CML history into your Signature

 

02/2010 Gleevec 400mg

2011 Two weakly positives, PCRU, weakly positive

2012 PCRU, PCRU, PCRU, PCRU

2013 PCRU, PCRU, PCRU, weakly positive

2014 PCRU, PCRU, PCRU, PCRU (12/07 began dose reduction w/each continuing PCRU)

2015 300, 250, 200, 150

2016 100, 50/100, 100, 10/17 TFR

2017 01/17 TFR, 04/18 TFR, 07/18 TFR 0.0012, 08/29 TFR 0.001, 10/17 TFR 0.000

2018 01/16 TFR 0.0004 ... next quarterly PCR 04/17

 

At the earliest opportunity, and whenever possible, lower your TKI dosage; TKIs are toxic drugs and the less we take longterm the better off we are going to be ... this is especially true for older adults.  

 

In hindsight I should have started my dosage reduction two years earlier; it might have helped minimize some of the longterm cumulative toxic effects of TKIs that I am beset with.  

 

longterm side-effects Peripheral Artery Disease - legs (it's a bitch); continuing shoulder problems, right elbow inflammation.   GFR and creatinine vastly improved after stopping Gleevec.

 

Cumulative Gleevec dosage estimated at 830 grams

 

Taking Gleevec 400mg an hour after my largest meal of the day helped eliminate the nausea that Gleevec is notorious for.  

 

Trey's CML BlogStopping - The OddsStop Studies - Discussion Forum Cessation Study

Big PhRMA - Medicare Status - Social Security Status - Deficit/Debt


#5 Widgeonus

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Posted 12 January 2015 - 12:18 PM

 The doc said 100 mg cost the same as a 400mg. and your not suppose to break a 400mg into.

 

 

And my doc prescribes me 45 400mg pills for a 30 day supply and has me cut 15 of the pills in half. 

 

Anyone know if this should or shouldn't be done?



#6 hannibellemo

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Posted 12 January 2015 - 12:35 PM

Widgeonous,

 

You can cut pills in half they just taste like crap!

 

According to the ACA, the "grandfathered plan" policy was a provision of the ACA designed to protect existing plans. A grandfathered plan is any policy in existence before March 23, 2010, when the ACA became law.  Grandfathered plans must eliminate lifetime benefit caps, offer coverage to dependent children over age 26 and eliminate pre-existing condition exclusions in 2014, but they are exempt from most other ACA reforms."

 

Pat


Pat

 

"You can't change the direction of the wind but you can adjust your sails."

DX 12/08; Gleevec 400mg; liver toxicity; Sprycel 100mg.; CCyR 4/10; MMR 8/10; Pleural Effusion 2/12; Sprycel 50mg. Maintaining MMR; 2/15 PCRU; 8/16 drifting in and out of undetected like a wave meeting the shore. Retired 12/23/2016! 18 months of PCRU, most recent at Mayo on 7/25/17 was negative at their new sensitivity reporting of 0.003.<p>


#7 Floa7

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Posted 12 January 2015 - 02:49 PM

Widgeonous,

 

You can cut pills in half they just taste like crap!

 

According to the ACA, the "grandfathered plan" policy was a provision of the ACA designed to protect existing plans. A grandfathered plan is any policy in existence before March 23, 2010, when the ACA became law.  Grandfathered plans must eliminate lifetime benefit caps, offer coverage to dependent children over age 26 and eliminate pre-existing condition exclusions in 2014, but they are exempt from most other ACA reforms."

 

Pat


1 2012 CML detected Started Gleevec 400 mg

In nov 2014 my pcr started to rise by Feb I stopped Gleevec and went onto

2 2015 Tasigna 600 mg/day

I have been PCRU for 2 years and stopped Tasigna 4 7 2017

5 8 2017 results 0.008

5 30 2017 results 0.028 

6 30 2017 results 0.3, I have restarted the Tasigna because it went above 0.1 

 

My son

11 2011 CML detected Started Gleevec 400 mg

He went 2 1/2 years on gleevec and lost PCRU

Started Sprycel went PCRU for 2 years and stopped the Sprycel, went back for 3 month checkup and PCR was 8.0

He went back onto Sprycel and now is PCRU again

3 16 2017 results 0.008

6 1 2017 results 0.002


#8 Floa7

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Posted 12 January 2015 - 02:58 PM

My son also has CML and his doc had him cut pills in half. But it says on my prescription bottle to not to cut them. But my doc wants me to fill one for the 100mg besides the 400mg one.

 

I phoned my union hall and talked to the insurance rep and I will be maxed out at 400K, since the policy was from 1996 and they could not change my cap. She said they had increased the cap on policies that were not so old.


1 2012 CML detected Started Gleevec 400 mg

In nov 2014 my pcr started to rise by Feb I stopped Gleevec and went onto

2 2015 Tasigna 600 mg/day

I have been PCRU for 2 years and stopped Tasigna 4 7 2017

5 8 2017 results 0.008

5 30 2017 results 0.028 

6 30 2017 results 0.3, I have restarted the Tasigna because it went above 0.1 

 

My son

11 2011 CML detected Started Gleevec 400 mg

He went 2 1/2 years on gleevec and lost PCRU

Started Sprycel went PCRU for 2 years and stopped the Sprycel, went back for 3 month checkup and PCR was 8.0

He went back onto Sprycel and now is PCRU again

3 16 2017 results 0.008

6 1 2017 results 0.002


#9 Buzzm1

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Posted 30 January 2015 - 08:28 PM

I checked the price on Gleevec 100mg (100 pills) today.

 

$8,311.65 or $83.12/100mg pill at Kaiser

 

there is plenty of time for more price increases before Gleevec goes generic in February, 2016

 

 BIG PhRMA http://bit.ly/msN6D4

For the benefit of yourself and others please add your CML history into your Signature

 

02/2010 Gleevec 400mg

2011 Two weakly positives, PCRU, weakly positive

2012 PCRU, PCRU, PCRU, PCRU

2013 PCRU, PCRU, PCRU, weakly positive

2014 PCRU, PCRU, PCRU, PCRU (12/07 began dose reduction w/each continuing PCRU)

2015 300, 250, 200, 150

2016 100, 50/100, 100, 10/17 TFR

2017 01/17 TFR, 04/18 TFR, 07/18 TFR 0.0012, 08/29 TFR 0.001, 10/17 TFR 0.000

2018 01/16 TFR 0.0004 ... next quarterly PCR 04/17

 

At the earliest opportunity, and whenever possible, lower your TKI dosage; TKIs are toxic drugs and the less we take longterm the better off we are going to be ... this is especially true for older adults.  

 

In hindsight I should have started my dosage reduction two years earlier; it might have helped minimize some of the longterm cumulative toxic effects of TKIs that I am beset with.  

 

longterm side-effects Peripheral Artery Disease - legs (it's a bitch); continuing shoulder problems, right elbow inflammation.   GFR and creatinine vastly improved after stopping Gleevec.

 

Cumulative Gleevec dosage estimated at 830 grams

 

Taking Gleevec 400mg an hour after my largest meal of the day helped eliminate the nausea that Gleevec is notorious for.  

 

Trey's CML BlogStopping - The OddsStop Studies - Discussion Forum Cessation Study

Big PhRMA - Medicare Status - Social Security Status - Deficit/Debt


#10 chriskuo

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Posted 31 January 2015 - 02:52 AM

Novartis wants to encourage patients to switch to Tasigna before Gleevec goes generic.  If the benefit somebody is getting from Gleevec as they are from Gleevec, from Novartis perspective, the value of the drug is the same.  Most Americans do not pay retail price for drugs.

 

If they did, they would be political pressure for the government to negotiate drug costs as happens is most other countries.   Essentially, the US insurance companies and their customers are financing the drug companies research costs and profits.



#11 Buzzm1

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Posted 31 January 2015 - 09:16 AM

Novartis Gleevec sales were $4.7 billion in 2014; 

Novartis Tasigna sales were $1.5 billion in 2014

 

Novartis Gleevec sales will be under increasing pressure in 2015 from generics http://bit.ly/1vkc42d

especially in 2016, when generic Gleevec (imatinib) finally becomes available in the U.S.

 

Barring a patient's failure to reach MMR/PCRU on Gleevec, that's the primary reason Novartis wants to switch Gleevec users over to patent-protected higher-priced Tasigna. It's about their bottom line.

 

Plus, there are now how many other CML TKI drugs competing for market share?

 

People pay for the cost of drugs, either directly, or indirectly, some more than others ... through copays, insurance payments, employee benefits, and taxes

 

insurance companies are simply middlemen, raking their 20% off the top  ... 


For the benefit of yourself and others please add your CML history into your Signature

 

02/2010 Gleevec 400mg

2011 Two weakly positives, PCRU, weakly positive

2012 PCRU, PCRU, PCRU, PCRU

2013 PCRU, PCRU, PCRU, weakly positive

2014 PCRU, PCRU, PCRU, PCRU (12/07 began dose reduction w/each continuing PCRU)

2015 300, 250, 200, 150

2016 100, 50/100, 100, 10/17 TFR

2017 01/17 TFR, 04/18 TFR, 07/18 TFR 0.0012, 08/29 TFR 0.001, 10/17 TFR 0.000

2018 01/16 TFR 0.0004 ... next quarterly PCR 04/17

 

At the earliest opportunity, and whenever possible, lower your TKI dosage; TKIs are toxic drugs and the less we take longterm the better off we are going to be ... this is especially true for older adults.  

 

In hindsight I should have started my dosage reduction two years earlier; it might have helped minimize some of the longterm cumulative toxic effects of TKIs that I am beset with.  

 

longterm side-effects Peripheral Artery Disease - legs (it's a bitch); continuing shoulder problems, right elbow inflammation.   GFR and creatinine vastly improved after stopping Gleevec.

 

Cumulative Gleevec dosage estimated at 830 grams

 

Taking Gleevec 400mg an hour after my largest meal of the day helped eliminate the nausea that Gleevec is notorious for.  

 

Trey's CML BlogStopping - The OddsStop Studies - Discussion Forum Cessation Study

Big PhRMA - Medicare Status - Social Security Status - Deficit/Debt


#12 Buzzm1

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Posted 28 May 2015 - 01:54 PM

I checked the price on Gleevec 100mg (100 pills) today.

 

$9,132.85 or $91.33/100mg pill at Kaiser

 

up 10% from January ($8,311.65 or $83.12/100mg)

 

anyone have the current 400mg price? 


For the benefit of yourself and others please add your CML history into your Signature

 

02/2010 Gleevec 400mg

2011 Two weakly positives, PCRU, weakly positive

2012 PCRU, PCRU, PCRU, PCRU

2013 PCRU, PCRU, PCRU, weakly positive

2014 PCRU, PCRU, PCRU, PCRU (12/07 began dose reduction w/each continuing PCRU)

2015 300, 250, 200, 150

2016 100, 50/100, 100, 10/17 TFR

2017 01/17 TFR, 04/18 TFR, 07/18 TFR 0.0012, 08/29 TFR 0.001, 10/17 TFR 0.000

2018 01/16 TFR 0.0004 ... next quarterly PCR 04/17

 

At the earliest opportunity, and whenever possible, lower your TKI dosage; TKIs are toxic drugs and the less we take longterm the better off we are going to be ... this is especially true for older adults.  

 

In hindsight I should have started my dosage reduction two years earlier; it might have helped minimize some of the longterm cumulative toxic effects of TKIs that I am beset with.  

 

longterm side-effects Peripheral Artery Disease - legs (it's a bitch); continuing shoulder problems, right elbow inflammation.   GFR and creatinine vastly improved after stopping Gleevec.

 

Cumulative Gleevec dosage estimated at 830 grams

 

Taking Gleevec 400mg an hour after my largest meal of the day helped eliminate the nausea that Gleevec is notorious for.  

 

Trey's CML BlogStopping - The OddsStop Studies - Discussion Forum Cessation Study

Big PhRMA - Medicare Status - Social Security Status - Deficit/Debt


#13 Dom

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Posted 29 May 2015 - 07:08 AM

GoodRX.com finds Gleevec 400 for 30 days priced at $9,440 at Target and Walgreens. That site also says it will go generic in July 2015.

Diagnosed in February 2014. Started Imatinib 400 in April.
2014:     3.18     0.91
2015:     0.22     0.16     0.04     0.55
2016:     0.71     0.66

(Started Imatinib 600 in April 2016)
2016:     0.42     0.13     0.45
2017:     0.17     0.06     0.10     0.06     0.34


#14 SUE

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Posted 29 May 2015 - 04:50 PM

There simply is no excuse for the outrageous prices that the pharmaceutical companies charge for our medications.  Our tax dollars pay for much of their research.

 

They do it because our elected representatives refuse to stop them.

 

They do it because they can.

 

Sue


Dx  April 2013, FISH 62,  BMB not enough for PCR test; put on Gleevec 400;

 August 2013, FISH 8.7;

Oct 2013, FISH 5.6

Stopped Gleevec Nov 2013 for 6 weeks due to terrible side effects; Jan 2014 started Sprycel 50mg;

Feb, 2014 PCR  6.8

May,2014  PCR   .149

Aug, 2014 PCR    .015

Nov. 2014 PCRU

March, 2016  went down to 40mg Sprycel

Oct. 2016   stopped Sprycel for a couple weeks due to concern about shortness of breath.  Echo showed mild PAH.

Nov 1 2016  resumed Sprycel 20 mg daily 

Dec 2016  PCRU

March 2017  PCR 0.020

May 2017     PCRU

Sept  2017   PCRU

Dec    2017  PCRU

 


#15 Buzzm1

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Posted 29 May 2015 - 06:09 PM

GoodRX.com finds Gleevec 400 for 30 days priced at $9,440 at Target and Walgreens. That site also says it will go generic in July 2015.

Dom, Gleevec (Imatinib) is scheduled to go generic in the U.S. Feb. 1, 2016

 

Price Check: Anyone else taking Gleevec 100mg?

 

There simply is no excuse for the outrageous prices that the pharmaceutical companies charge for our medications.  Our tax dollars pay for much of their research.

 

They do it because our elected representatives refuse to stop them.

 

They do it because they can.

 

Sue

 

Couldn't agree with you more Sue

 

BIG PhRMA http://bit.ly/msN6D4

 

Buzz


For the benefit of yourself and others please add your CML history into your Signature

 

02/2010 Gleevec 400mg

2011 Two weakly positives, PCRU, weakly positive

2012 PCRU, PCRU, PCRU, PCRU

2013 PCRU, PCRU, PCRU, weakly positive

2014 PCRU, PCRU, PCRU, PCRU (12/07 began dose reduction w/each continuing PCRU)

2015 300, 250, 200, 150

2016 100, 50/100, 100, 10/17 TFR

2017 01/17 TFR, 04/18 TFR, 07/18 TFR 0.0012, 08/29 TFR 0.001, 10/17 TFR 0.000

2018 01/16 TFR 0.0004 ... next quarterly PCR 04/17

 

At the earliest opportunity, and whenever possible, lower your TKI dosage; TKIs are toxic drugs and the less we take longterm the better off we are going to be ... this is especially true for older adults.  

 

In hindsight I should have started my dosage reduction two years earlier; it might have helped minimize some of the longterm cumulative toxic effects of TKIs that I am beset with.  

 

longterm side-effects Peripheral Artery Disease - legs (it's a bitch); continuing shoulder problems, right elbow inflammation.   GFR and creatinine vastly improved after stopping Gleevec.

 

Cumulative Gleevec dosage estimated at 830 grams

 

Taking Gleevec 400mg an hour after my largest meal of the day helped eliminate the nausea that Gleevec is notorious for.  

 

Trey's CML BlogStopping - The OddsStop Studies - Discussion Forum Cessation Study

Big PhRMA - Medicare Status - Social Security Status - Deficit/Debt


#16 Dom

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Posted 29 May 2015 - 08:59 PM

Buzz, I just did a little research, and it seems we're both right. Gleevec goes off patent in July 2015, but generics are not allowed to start until February 2016. I have no way to explain the time delay there.

Pharmas deserve to make money, but $10,000 a month for a life saving drug seems ... Excessive.

Diagnosed in February 2014. Started Imatinib 400 in April.
2014:     3.18     0.91
2015:     0.22     0.16     0.04     0.55
2016:     0.71     0.66

(Started Imatinib 600 in April 2016)
2016:     0.42     0.13     0.45
2017:     0.17     0.06     0.10     0.06     0.34


#17 chriskuo

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Posted 30 May 2015 - 02:12 AM

Sue, 

 

You are right and it is on us as citizens.  The US may be the only developed country where the elected representatives refuse to allow the government to negotiate prices with the pharma companies.

 

The pharma companies would charge more in other countries if their governments did not negotiate them down.

 

However, it is fair to note that virtually nobody pays the US list price.  Insurance companies do negotiate lower prices and the copays for the patient are usually a very small percentage of what the insurers actually pay.  In the catastrophic phase of Medicare Part D, insurance companies must limit their copay to 5%.



#18 SUE

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Posted 30 May 2015 - 07:35 PM

Hi Chris,

 

I think many citizens have tried to change the drug prices.  More than 2 years ago many doctors wrote about the situation--

http://www.whiteoutp...ancer-patients/

But the prices continue to go up.  

 

I have Medicare Part D, and in January I paid over $2000 for a 30 day supply of Sprycel 50mg.  When I went into the catastrophic phase, I paid more than $285 for a 30 day supply.  Every time I go to the pharmacy to pick up my Sprycel, the pharmacist asks in hushed tones, "Do you know what the price of this medication is?"

 

And the taxpayers are picking up the difference between what I paid and what the companies charge.  We are all paying the US list price.  

 

Sue


Dx  April 2013, FISH 62,  BMB not enough for PCR test; put on Gleevec 400;

 August 2013, FISH 8.7;

Oct 2013, FISH 5.6

Stopped Gleevec Nov 2013 for 6 weeks due to terrible side effects; Jan 2014 started Sprycel 50mg;

Feb, 2014 PCR  6.8

May,2014  PCR   .149

Aug, 2014 PCR    .015

Nov. 2014 PCRU

March, 2016  went down to 40mg Sprycel

Oct. 2016   stopped Sprycel for a couple weeks due to concern about shortness of breath.  Echo showed mild PAH.

Nov 1 2016  resumed Sprycel 20 mg daily 

Dec 2016  PCRU

March 2017  PCR 0.020

May 2017     PCRU

Sept  2017   PCRU

Dec    2017  PCRU

 


#19 Buzzm1

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Posted 30 May 2015 - 09:07 PM

snip

http://www.whiteoutp...ancer-patients/

But the prices continue to go up.  

 

snip

Sue, excellent article, great table at the end of the article

 

Price gouging in the United States

2012/2013 price per year

Country                     Imatinib               Nilotinib               Dasatinib

US                             $92k                       $115k                    $123k

Germany                    $54k                       $60k                       $90k

UK                             $33k                       $33k                       $48k

Canada                       $46k                       $48k                       $62k

Norway                       $50k                       $61k                       $82k

France                        $40k                       $51k                       $71k

Italy                            $31k                       $43k                       $54k

South Korea                $28k                       $26k                       $22k

Mexico                        $29k                       $39k                       $49k

Argentina                     $52k                       $73k                       $80k

Australia                      $46k                       $53k                       $60k

Japan                          $43k                       $55k                       $72k

China                           $46k                       $75k                       $61k

Russia                         $24k                       $48k                       $56k

South Africa                 $43k                       $28k                       $54k


For the benefit of yourself and others please add your CML history into your Signature

 

02/2010 Gleevec 400mg

2011 Two weakly positives, PCRU, weakly positive

2012 PCRU, PCRU, PCRU, PCRU

2013 PCRU, PCRU, PCRU, weakly positive

2014 PCRU, PCRU, PCRU, PCRU (12/07 began dose reduction w/each continuing PCRU)

2015 300, 250, 200, 150

2016 100, 50/100, 100, 10/17 TFR

2017 01/17 TFR, 04/18 TFR, 07/18 TFR 0.0012, 08/29 TFR 0.001, 10/17 TFR 0.000

2018 01/16 TFR 0.0004 ... next quarterly PCR 04/17

 

At the earliest opportunity, and whenever possible, lower your TKI dosage; TKIs are toxic drugs and the less we take longterm the better off we are going to be ... this is especially true for older adults.  

 

In hindsight I should have started my dosage reduction two years earlier; it might have helped minimize some of the longterm cumulative toxic effects of TKIs that I am beset with.  

 

longterm side-effects Peripheral Artery Disease - legs (it's a bitch); continuing shoulder problems, right elbow inflammation.   GFR and creatinine vastly improved after stopping Gleevec.

 

Cumulative Gleevec dosage estimated at 830 grams

 

Taking Gleevec 400mg an hour after my largest meal of the day helped eliminate the nausea that Gleevec is notorious for.  

 

Trey's CML BlogStopping - The OddsStop Studies - Discussion Forum Cessation Study

Big PhRMA - Medicare Status - Social Security Status - Deficit/Debt


#20 chriskuo

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Posted 30 May 2015 - 11:44 PM

Buzz,

 

The title "price gouging" implies that the drug companies are over-charging US patients.  What the chart shows mostly is that other governments are negotiating lower prices.  Some of the difference may be related to lower incomes in the other countries, but if our representatives allowed the government to negotiate prices, the prices in the US would be much lower.






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