I received my December PCR and bone marrow.
PCR, for the second time in a row, is "undetected". So that's good.
But my bone marrow shows 95% of my cells are Trisomy 8, up from 65% a year ago when my bone marrow was last checked.
The only thing I can infer is that is the reason I still have myelosuppression (minor, but not insignificant).
Reading on Trisomy 8 seems to relate to MDS. I don't have MDS...at least not yet.
I only take 20mg Sprycel.
Bone marrow results:
BONE MARROW DIFFERENTIAL
BM Method SMEAR
Adequacy Limited sample
Site Right Posterior Iliac Crest
Total cells counted 300
Blasts 0 % (0-5)
Progranulocytes 1 % L (2-8)
Myelocytes 7 % (5-20)
Metamyelocytes 8 % L (13-32)
Granulocytes 34 % H (7-30)
Eosinophils 1 % (0-4)
Lymphocytes 18 % H (3-17)
Plasma cells 0 % (0-2)
Monocytes 5 % (0-5)
Reticulum Cells 0 % (0-2)
Pronormoblasts 1 % (1-8)
Normoblasts 25 % (7-32)
M:E Ratio 2.0 L (3-4)
NOTE: Normal ranges apply to adults only. Call
the Diagnostic Bone Marrow Laboratory
for pediatric reference ranges.
BONE MARROW CLOT
Quality: Inadequate, no particles
BONE MARROW SMEARS/TOUCH PREPS
Quality: Limited with aparticulate and hemodilution
Granulocytes: Sequential maturation, no overt dysplasia.
Erythrocytes: Sequential maturation, no overt dysplasia
Megakaryocytes: Not seen
Lymphocytes: Not increased.
Blasts: Not increased.
BONE MARROW DIAGNOSIS
Bone marrow, right posterior iliac crest, clot section, aspirate smears:
Limited specimen with trilineage hematopoiesis