Good grief, it is complicated enough for newbies like me. I go for my three month Fish and PCR on Wednesday. I am so nervous. What should I hope for and what should I expect? What is reasonable? My CBC was all normal. My RDW was a little high but only by 0.2.
Does any one know what standard Levine's Cancer Institute in Charlotte, NC uses? These are all questions I will ask the doc on Wednesday but doesn't hurt to be informed before hand.
Can someone tell me what PCRU is?
Started by
jmoorhou
, Dec 25 2014 07:28 PM
25 replies to this topic
#21
rcase13
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Posted 03 January 2015 - 11:35 AM
10/01/2014 100% Diagnosis (WBC 278k, Blasts 6%, Spleen extended 20cm)
01/02/2015 0.06% Tasigna 600mg
04/08/2015 0.01% Tasigna 600mg
07/01/2015 0.01% Tasigna 600mg
10/05/2015 0.02% Tasigna 600mg
01/04/2016 0.01% Tasigna 600mg
04/04/2016 PCRU Tasigna 600mg
07/18/2016 PCRU Tasigna 600mg
10/12/2016 PCRU Tasigna 600mg
01/09/2017 PCRU Tasigna 600mg
04/12/2017 PCRU Tasigna 600mg
10/16/2017 PCRU Tasigna 600mg
01/15/2018 PCRU Tasigna 600mg
Cancer Sucks!
#22
rcase13
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Posted 12 January 2015 - 03:57 PM
Ok so today I got my 3 month results and I am FISH negative and PCR of 0.06%. I understand that to be MMR. Yeah!!!! My lab here in Charlotte NC is on the IS standard.
So my next step is PCRU or CMR. So what is that exactly? anything less than .005%? At what point do the new PCR tests say undetectable? I think my doctor said they can measure a 4.5 log reduction. I know a 4 log reduction would be .01 so is 4.5 log reduction .005?
I am just curious. I am happy being 99.94% cancer free!
10/01/2014 100% Diagnosis (WBC 278k, Blasts 6%, Spleen extended 20cm)
01/02/2015 0.06% Tasigna 600mg
04/08/2015 0.01% Tasigna 600mg
07/01/2015 0.01% Tasigna 600mg
10/05/2015 0.02% Tasigna 600mg
01/04/2016 0.01% Tasigna 600mg
04/04/2016 PCRU Tasigna 600mg
07/18/2016 PCRU Tasigna 600mg
10/12/2016 PCRU Tasigna 600mg
01/09/2017 PCRU Tasigna 600mg
04/12/2017 PCRU Tasigna 600mg
10/16/2017 PCRU Tasigna 600mg
01/15/2018 PCRU Tasigna 600mg
Cancer Sucks!
#23
scuba
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Posted 12 January 2015 - 04:01 PM
Ok so today I got my 3 month results and I am FISH negative and PCR of 0.06%. I understand that to be MMR. Yeah!!!! My lab here in Charlotte NC is on the IS standard.
So my next step is PCRU or CMR. So what is that exactly? anything less than .005%? At what point do the new PCR tests say undetectable? I think my doctor said they can measure a 4.5 log reduction. I know a 4 log reduction would be .01 so is 4.5 log reduction .005?
I am just curious. I am happy being 99.94% cancer free!
Rcase - when were you diagnosed? 3 months ago?
Diagnosed 11 May 2011 (100% FiSH, 155% PCR)
with b2a2 BCR-ABL fusion transcript coding for the 210kDa BCR-ABL protein
Sprycel: 20 mg per day - taken at lights out with Quercetin and/or Magnesium Taurate
6-8 grams Curcumin C3 complex.
2015 PCR: < 0.01% (M.D. Anderson scale)
2016 PCR: < 0.01% (M.D. Anderson scale)
March 2017 PCR: 0.01% (M.D. Anderson scale)
June 2017 PCR: "undetected"
September 2017 PCR: "undetected"
#24
rcase13
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Posted 12 January 2015 - 04:05 PM
Yes 3 months ago. I was diagnosed 9/25/2014 and Started Tasigna on October 1st.
10/01/2014 100% Diagnosis (WBC 278k, Blasts 6%, Spleen extended 20cm)
01/02/2015 0.06% Tasigna 600mg
04/08/2015 0.01% Tasigna 600mg
07/01/2015 0.01% Tasigna 600mg
10/05/2015 0.02% Tasigna 600mg
01/04/2016 0.01% Tasigna 600mg
04/04/2016 PCRU Tasigna 600mg
07/18/2016 PCRU Tasigna 600mg
10/12/2016 PCRU Tasigna 600mg
01/09/2017 PCRU Tasigna 600mg
04/12/2017 PCRU Tasigna 600mg
10/16/2017 PCRU Tasigna 600mg
01/15/2018 PCRU Tasigna 600mg
Cancer Sucks!
#25
scuba
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Posted 12 January 2015 - 04:11 PM
Yes 3 months ago. I was diagnosed 9/25/2014 and Started Tasigna on October 1st.
What was your FISH at diagnosis?
Diagnosed 11 May 2011 (100% FiSH, 155% PCR)
with b2a2 BCR-ABL fusion transcript coding for the 210kDa BCR-ABL protein
Sprycel: 20 mg per day - taken at lights out with Quercetin and/or Magnesium Taurate
6-8 grams Curcumin C3 complex.
2015 PCR: < 0.01% (M.D. Anderson scale)
2016 PCR: < 0.01% (M.D. Anderson scale)
March 2017 PCR: 0.01% (M.D. Anderson scale)
June 2017 PCR: "undetected"
September 2017 PCR: "undetected"
#26
rcase13
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Posted 12 January 2015 - 04:16 PM
Honestly I don't know. Basically 100% I think is what the doc said. My spleen was huge! My WBC was 278. My spleen still hurts 3 months later. I still can't sit in a chair without unbuttoning my jeans... Hopefully no one is looking! 
10/01/2014 100% Diagnosis (WBC 278k, Blasts 6%, Spleen extended 20cm)
01/02/2015 0.06% Tasigna 600mg
04/08/2015 0.01% Tasigna 600mg
07/01/2015 0.01% Tasigna 600mg
10/05/2015 0.02% Tasigna 600mg
01/04/2016 0.01% Tasigna 600mg
04/04/2016 PCRU Tasigna 600mg
07/18/2016 PCRU Tasigna 600mg
10/12/2016 PCRU Tasigna 600mg
01/09/2017 PCRU Tasigna 600mg
04/12/2017 PCRU Tasigna 600mg
10/16/2017 PCRU Tasigna 600mg
01/15/2018 PCRU Tasigna 600mg
Cancer Sucks!
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