Hang in there - we know exactly how you feel! I went through the same phase ... I'll share a little bit of my journey to help:
If I knew then what I knew now, I would've been so much calmer in the early months of treatment (I'm four years into Gleevec 400mg). Every pain, lump, bruise, etc. drove total anxiety and paranoid thinking that (at times) completely crippled me ... and even worse, caused my family a lot of unnecessary grief. Week 1, I thought I was going to crumble and die at any moment. Week 2, I thought my liver was going to fail. Week 3, I thought my neutrophil count would drop to 0 and kill me, etc. Sound familiar?
Short story - Most of us went through the very same phase that you're going through now, so we know how you feel. But repeat after me: "It's going to be okay ... control what I can control and move on with my life." Write that on a piece of paper, laminate it and put it under your pillow. It will help! One of the first pieces of advice I received in the beginning of my CML journey was "chill and take the pill". That is the part that we can control, so we do that diligently, build a trusting relationship with a great care team, and we move on with life as we adjust to our "new normal".
For me personally, it took about 9 months to finally calm down (for the most part). What worked (and continues to work) for me:
1. Exercise - Anything: walking, running, cycling, gym, yoga, stretching, etc. It's a great way to calm the mind and it's a good treatment monitor as well. If you're breathing well and able to exercise and stay in shape, then it builds confidence in your mind that you're going to outlive CML. Find something that works for you and get into the routine. Just take it easy and don't push yourself too hard. I went a bit overboard and have suffered some injuries from intense running and road cycling, so an important lesson learned there - we generally heal slower when on TKI medications, so know your limits.
2. Wellness Appointment - Check with your onc and learn more about wellness specialists. I am treated at Emory in Atlanta, and they have a wonderful team that works with cancer patients on wellness plans. Some of their recommendations helped, some didn't, but I believe their approach to treatment (always mind/soul first, and medication only if absolutely needed) was a huge help for me. This is a chronic condition, so I felt it was important to pursue expert advice in this area so I could figure out how to live with this monkey on my back.
3. Meditation - I am very bad at this , but I do incorporate breathing exercises into my daily protocol that help calm the mind on a daily basis. An easy one to start with: If you start to feel a bit anxious, try putting a finger on one nostril, breathe in slow and deep, remove the finger and breathe out fully, cover the other nostril, breathe in deep, remove the finger, and breathe out slowly (eyes closed, and finger "on" the nostril and not "in" the nostril, hahaha). Someone taught me this technique and I do find that it helps.
4. Medication - It's okay to consider some medication as an initial course of treatment to help balance/reset the chemicals in the brain and condition you to treat your own anxiety - the goal is to avoid a dependency on it. Even after four years, I sometimes use a little bit of medication if I feel like I'm losing the battle, and it can quickly get me over the hump (while working on 1, 2, 3). I have not encountered any drug interaction issues with Gleevec.
I hope this helps!