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pcr < 10% and not in MCyR. is it possible?


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#1 Lucas

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Posted 19 September 2014 - 04:38 PM

I was wondering: i thought that when you get below the 10% pcr you must be in a MCyR. I was below 10% in various tests since my 6 months (different labs), but my marrow was at 40% PH+. Is this possible? is it possible a mistake in the cytogenetic test? I'm probably moving to tasigna 800 mg in the next few weeks. Thanks in advance!



#2 Trey

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Posted 19 September 2014 - 09:34 PM

I would always trust the BMB cytogenetics more than the PCR, especially at higher levels. 

 

10% PCR is only 1 log reduction.  So the 40% BMB is about right.  1% PCR should be where the BMB goes to 0.



#3 Lucas

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Posted 20 September 2014 - 07:24 AM

Thanks, trey. I always thought that if i were below 10% (i were 6% or 3%) i must be with less than 36% PH+. cheers!






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