Hi all. I was on Gleevec for about a year and had every side effect known (well almost) and was having ok response. My onc then put me on Tasigna and was on it for 2 months before my insurance said I had to switch to Sprycel...unfortunately, in only two months I went to undetectable (yea). Was on Sprycel and immediately I went back to detectable with 4 straight months of increasing percentage (all IS) and terrible fatigue. Given the poor response and the fatigue we went back to Tasigna (waiting to see if insurance will approve this time). Two weeks ago I had an attack of Pancreatitis (worst pain I've EVER had). Wondering if anyone else has had Pancreatitis on TKIs. I now it is listed as a side effect on Tasigna but I had no indications the first time I was on it and I think I recall feeling some upper abdominal pain at the end of the Sprycel experiment.