In summary, my last 4 PCRs in order, (done every 3 months, so this is in the last 12 months):
<0.001 (same as 0 because that is how low the test claims to go).
It was exciting to reach 0 and then very depressing to lose it. However, since my sample is crazily sent to NH, USA from Chicago, I will guess that the <0.001 was an error or from a degarded sample.
I think your numbers look good. Please someone correct me if I am wrong, but I think even a .5 log increase at such low levels would likely not be significant. This would be due to the inaccuracy of the test and that it is reported in averages. As long as subsequent values bounce up and down, one would remain in the "safety zone". Like Pat said, the goal is 0.1 and lower (MMR).
I must confess, I write this also for my peace of mind. Knowing and emoting sometimes don't jive. I was depressed for days with my last PCR value.
I know this is debated, but I have read that low values have been found in people who do not have any signs of CML, (thus, healthy individuals). It seems their immune systems may recognize the rogue protein. Thus, keeping it low. So, a lifettime, (hopefully long), of low PCR values would mean the drug or the body is doing a good job, (as far as CML goes).
PCRs are different all over the world. Some are more sensitive than others. Depending on the machine, a value of PCRU or <0.001 may not be all that reliable. Thus, neither would upticks in the PCR mean disease progression.
I have to keep in mind that disease progression is not only a PCR value. One has to look at the cells too. Wish there was another way than BMB, but c'est la vie. What else better can be said to detach from this emotional rollercoaster?
May BMBs remain in our past forever!