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[elvis]

I started taking sprycel about 8-10 weeks back and have been progressively seeing decrease in RBC and Hemoglobin levels.  Also having some fluctuations in my liver enzymes.  Currently in MMR and was taking Tasigna before for 3.5 years.

Is this normal?  Should I worry looking at the numbers.  It is consistently and progressively going down.  What are my options?

Little concerned with this.  Any input or guidance is greatly appreciated.

Hemoglobin Levels

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05/16/2014	11.8 g/dl [13-17 g/dl]
05/02/2014	12.2 g/dl [13-17 g/dl]
04/18/2014	12.6 g/dl [13-17 g/dl]
04/08/2014	13.1 g/dl [13-17 g/dl]
04/01/2014	12.5 g/dl [13-17 g/dl]

RBC Levels

-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------

05/16/2014	3.75 M/mcL [4.2-5.6 M/mcL]
05/02/2014	3.96 M/mcL [4.2-5.6 M/mcL]
04/18/2014	4.16 M/mcL [4.2-5.6 M/mcL]
04/08/2014	4.26 M/mcL [4.2-5.6 M/mcL]
04/01/2014	4.17 M/mcL [4.2-5.6 M/mcL]

[Trey]

Except for the latest results the overall trends are stable enough.  Even so your results are not low enough to worry about unless they trend lower still.  You have not yet acclimated to the drug change.