Had my PCR draw to see if the upward trend continues or if it breaks. If it goes up I get a BMB and likely switch to Tasigna. Hoping it holds the line for now. I'm starting to wonder if biologically I am not processing Sprycel effectively. Perhaps I am grasping at straws but I know you need an acidic environment for Sprycel, which is why you can't take antacids or proton pump inhibitors. When I started Sprycel I had significant chest pains. After many evaluations the prevailing theory was that it was GI related. So I systematically changed my diet, ultimately eliminating all things that cause acid type symptoms, in particular I stopped eating all dairy. My side effects pretty much went away and soon after my numbers started to go up. I found it odd that as we increased my dosage my side effects never came back even as we got back up to 100, something we chalked up to me just "getting used to the drug". For Easter I cheated a little and I ate quite a bit of cheese earlier in the day and I had a rich piece of chocolate cake today. Tonight I have significant chest pains and a feeling in my chest like I have to cough. These are the same side effects I had early on. I know over the next couple of days if I watch what I eat the symptoms will go away. I'm now starting to wonder could my controlled diet also somehow impact my ability to process the drug? I know it sounds crazy but does it stand to reason if I don't have side effects maybe the drug isn't working? I mentioned to Dr, he didn't blow it off he just said there was no test he was aware of with Sprycel to check blood concentration levels so if anything it would just be a theory that we really couldn't prove. He sad at the end of the day it either works or it doesn't. I guess if I have to cause myself to have bad side effects for the drug to work that wouldn't be a good scenario anyway.
So for now I do the waiting game and see what the results look like when they come back.
Hope everyone is doing well