After four successful years of treatment on Sprycel, my Dad is showing signs of reactions. He was recently treated for a pleural effusion, it was drained and tested, no signs of infection or other disease. Within a few weeks, the fluid around his lungs has collected again and he will have another tap. Dr's have concluded that this is a side effect of his meds and have recommended to hold the dasatinib, be treated with a course of steroids (Medrol) and to be restarted on lower dose of dasatinib in the future. There is great reluctance to switch him to another med given the serious side effects he experienced after being newly diagnosed and which I have discussed on earlier posts.
His BRC-ABL is undetectable and we would like to keep it that way.
Has anyone else experience the same pleural effusion after so many years of treatment on Sprycel? Was your does lowered? Did your counts remain undetectable? Or, did you have to switch to another med? If so, was it a successful switch?
Many thanks in advance for sharing any information you have and I am wishing everyone good health.