Yes. I was diagnosed with chronic phase CML at the end of March 2011 -- got the "report to the ER immediately!" call from the doc on a Saturday afternoon about 3 hours after running a 5K road race with my kids. WBC = 155,000 at diagnosis that afternoon. Spleen size was normal.
1. Symptoms - Starting around November 2010, my runs started becoming slower and with increased breathing. Also around that time, I had occasional night sweats. At the time, I was in the middle of a work engagement that had me traveling from the east coast to west coast USA, so I was taking a Friday red-eye flight back home every other week and would be pretty short on sleep on the weekends. I really thought that the night sweats were nothing more than my body hitting the reset switch from jet lag. I visited my primary physician at the end of 2010 and complained about my slower running, but he examined me and sent me home with a "you're getting into your 40s, so your running is going to get slower" explanation (?). In January 2011, I started getting a "whoosh, whoosh" sound in my right ear that wouldn't go away, so I went back to my doc again and he suspected fluid around my eardrum and prescribed a simple nose inhaler. I tried that until the middle of February 2011, but the sound started getting a bit louder as the weeks progressed. Then, around early March, I started getting that "whoosh, whoosh" sound & sensation throughout my head, and my running continued to get slower. I also had moments where that sensation in my head would make me a little dizzy (?). The last straw was when I tried to do a speed workout at the track one weekend, and I found myself keeled over and completely out of breath after struggling through 4 laps. Each morning, I also started to get an extended-hangover feeling that didn't seem right, so I visited my primary doc yet again! At that point, in late March 2011, he finally decided to do some bloodwork as a precaution - this was on a Thursday morning. Then we got the fateful call on Saturday morning.
2. CT scans, etc. - Yes. I had an abdomen CT scan without contrast in late May 2011 after having some very painful symptoms in the area that freaked me out. I had only been on Gleevec 400mg for about 6 weeks, so the symptoms were either related to my body adjusting to the TKI, or perhaps stress/anxiety - or maybe both. I have also had several X-rays and two MRIs of my left ankle over the past 15 months because of a nasty running injury that required surgery at the end of July 2012. Once my bone marrow started recovering with TKI treatment, my running started speeding back up dramatically and it was awesome .... well, until I messed up my ankle. So despite the CT scan and MRIs over the past 2-1/2 years, I reached CCyR and a comfortable MMR over the first 9 months of Gleevec 400mg and have maintained it ever since. My next PCR test is next month (I'm on a 6-month testing cycle), so hopefully that's still the case!
Hope this is helpful -