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Gleevec and Ibuprofen

Started by CML2012 , Aug 23 2013 10:04 PM

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3 replies to this topic

#1 CML2012

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65 posts

LocationCharlotte North Carolina

Posted 23 August 2013 - 10:04 PM

For anyone taking Gleevec do not use ibuprofen, it blocks the Gleevec according to a study released earlier this year. I was given this information by my pharmacist. Just FYI. I use Aleve.

Diagnosed CML December 2012
Gleevec 400 mg
PCR 53%, 41%, 1.69%, 5.63% (Mutation test negative) September 2013
Sprycel 100 mg
PCR 1.1%, 0.2%, 0.2%, 0.6%, .09%, .06%, PCRU June 2015, PCRU Sept 2015, PCRU Dec 2015, 0.042% Mar 2016, 0.122% April 2016, 0.19% June 2016, 0.176% July 2016, .052% Sept 2016, .031% Nov 2016
Diagnosed Basel Skin Cancer December 2012, October 2014 (All cancer removed)
Diagnosed Melanoma April 2015 (All cancer removed)

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#2 critchhwc

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Posted 25 August 2013 - 09:18 PM

Just the kind of information I am compiling. Most nsaid's have the same drug interactions. If ibuprofen interferes with bio-availabilty of imatinib then most likely so does aleve, and the many others in the same class. There are several other drugs and foods that also interfere with imatinib. Tylenol and grapefruit juice are contra-indicated while on imatinib therapy.

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#3 Susan61

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LocationNew Jersey

Posted 25 August 2013 - 09:33 PM

Ibuprofen and aleve etc. can also cause kidney damage with too much use. I have CKD, and have not been able to take anything for years now. I suffer with my aches and pains. You have to be careful with anything, even too many vitamins can cause you more harm than good.

Be careful of anything you take. It can fix one thing and cause another. I have not had Tylenol or Grapefruit juice since I started Gleevec.

Susan