Hello to everyone,
I recently was switched from Sprycel to Ponatinib because of a mutation Q252H. My pcr was 13.186% on IS, thankfully after a month on ponatinib the pcr came down to 2.7788%, yay. Right before I found out about the increase, I started experiencing horrible bone pain in my legs and hips. I have been on ponatinib for a month in a half and still am experiencing this. At night, the pain becomes unbearable. It does not happen every night but the only relief I can get is soaking in a hot bath. Has anyone else dealt with this? Last night, I didn't get to sleep at all because of this. I do not know what to do. I told my doctor and she said it was stress related and could also be because of wearing flip flops. I think she is crazy this is severe pain equal to kidney stone pain! Any input?