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Two CML patients who subsequently developed features of essential thrombocythemia with JAK2-V617F


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#1 cousineg

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Posted 20 July 2013 - 11:59 AM

See Two CML patients who subsequently developed features of essential thrombocythemia with JAK2-V617F mutation while in complete cytogenetic remission after treatment with imatinib mesylate.

http://www.ncbi.nlm....pubmed/23613267

See also

http://www.cmleukemi...ythemia-et.html



#2 Trey

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Posted 20 July 2013 - 04:35 PM

I believe it says they were diagnosed with CML also having the JAK2 mutation, then went into CCyR, then developed "features" of ET (which may not actually be ET, maybe just high platelets).  That is different than gaining a subsequent additional mutation.






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