My EST GFR MDRD IS 56 and my EST CRCL CG is only 49. Remarks; ""Decrease in GFR If estimated MDRD/CRCL chronically IS in this range thIS corresponds to Stage 3 CKD, Chronic Kidney Disease, this has been going on for about 2 or 3 years, I think.
Last Thursday I ask my Hematologist/Oncologist about this, and he said it was BulL/SH, as Creatine and Bun were normal, it was Ok. He didn't like the formula they est for GFR. You can go on the internet and key in your age, female weight, and creatinine and it will give you your GFR. Some reports say Creatinie will stay in normal range until you kidney function is below 60 %. It is hard to know what to believe and understand it all.
I called two kidney specialist / Nephrologist, but they won't see me unless I have a doctor referral. I called Medicare and they said I don't need a referral. But it seems the Nephrologist specilist wants the doctors referral. So I have appointment tomorrow, Mon, with primary doc and I am going to insist on a referral. After kidney specialist I am going to St Vincent Cardio. I have lost 40 lbs and discontinued blood pressure med's Metoprolo because blood pressure got to low from losing weight. I take Triamterene/hctz 37/5/25, it has 37mg of blood pressure and 25 mg of diuretic. I am suppose to take it as need, my hands, mainly the left one will swell badly, I have trouble using the hand, so I take the Triam/Diurectic and blood pressure drops below 100 but the swelling goes down. Also seem like when my hands swell my hips and knees hurt, wonderful if swelling and blood pressure issues are from bad kidney filter??. I have also tried getting The triamterene/hctz pill form instead of capsule, so I can try cutting them in half. Nothing works. My blood pressure may even be normal but the swelling, make it to where I can't use my left hand very well and my joint will bother me. So I don't know if it from a kidney problem or not. Seems like everyone is just guessing?
Meanwhile I ask onc to switch to Sprycel 50mg for about 3 month and if I am at the low CCYR to leave it at 50mg, if not I would go as high as 70mg. The standard protocol is maybe start at 50mg for a week then straight to 100mg. But I will try an stay at 50mg. He was not happy but said he would check with insurance. I haven't take Gleevec since a week ago Friday as I had a boil on my left elbow and my arm swelled up so am on antibiotic, he wasn't real happy about not taking Gleevec, but if switch TKI need to take a vacation anyhow.
I don't want to lose my kidneys!!!! I just got back from a 4 week vacatin in Florida, and stayed 1 week with a school chum I haven't seen in over 50 years. She has been on a kidney dialyses for over a year and has a donor friend, that is if the donor passes all her test, she will get a new kidne in a few months. . I was in better shape than my friend. She starts on dyalsis at 6: 30am for about 4 hours, comes home, they pulled 7 lbs of fluid off so she had to stay until they broght her bl pressure up, then comes home, sleeps the rest of the day, gets up a couple of hours goes back to bed. Next day tries to run a few errands but has to get sit or lay down somewhere. She will get a donor. I can't imagine anyone giving a kidney to somene 65 years old with CMl and taking drugs that will probably shut another good kidney down.
If I have to go on a dialyses I would rather just thru in the towel. I have read several different article and it is hard to know what to believe. I called the pharmacist and he said Gleevec can cause kidney problem. Been on Gleevec 8 years.
What is your opinion, as I know you have been on Gleevec a long time 8 years, and have had a low GFR for two or three years and lost my Gall bladder after 2 years of Gleevec, Sugeon said gall bladder looked good I guess it just quit working.
1. I need to see a kidney spealist, 2. I need to go to St Vencent Cardio, one of the best Cardio hospital in the world. 3. Probably change TKI at a low dose only.
Well I see this turned out quite long!!