I had my 6 month bmb on Monday, and my onc called today with some preliminary results. The lab is apparently taking their sweet time, so I will not have my PCR or my full chromosome test until next Wednesday or Thursday. Even my onc was "displeased", and he is incredibly diplomatic!
Just FYI I take 600mg of Gleevec daily, and I think I have been fairly lucky so far with side effects. I have occasional muscle cramping, and I definitely get hit by the Gleevec fog a couple of days a week. My CK has been borderline high (between 300-400) in the past 6 weeks, but I am not symptomatic, so they are just keeping an eye on it. Here are my results so far:
Diagnosis - PCR 71.5% 16/20 chromosomes positive (80%)
3 mo - PCR 1.83% 2/20 chromosomes positive (10%) FISH 4.5%
I do not remember my onc ever mentioning my FISH scores before, but he told me today that my FISH was negative (it was 4.5% at 3mo, which I don't remember hearing at the time). He explained that this is certainly good news, but that it does not guarantee that my chromosomes will all be negative. I would assume that it is certainly a good thing that this test is now negative and everything is moving in the right direction.
Could yall help me understand how much emphasis to place on FISH? I am just trying to put all of the pieces into perspective as I move through this disease. I don't want to over-celebrate a negative FISH, but I don't want to assume that it is no big deal either. Typically I don't have a problem understanding medical tests and results, but I am having a hard time putting all of the pieces together these days. (Can I blame the Gleevec?? Ha!)
Many thanks for your help and support.