Its been a while since I've posted about my husband. He was diagnosed summer of 2011 and had a suboptimal response to Gleevec and was switched to Sprycel by his oncologist. Had a HORRIBLE response and we decided it was time to go see Dr. Cortes. Cortes put him back on Gleevec with goal of cytogenic remission at one year. That hasn't happened and we just got his BCR/ABL report from MDA and it jumped from 1.2 in August to 34.45. We're waiting to hear back from additional mutation reports they're running - assuming he will be switched to Ponatinib or Bosutinib.
Here's my question and I would love your help. My husband has dipped for 30 years - disgusting, horrible habit and he HAS to quit. Does anyone have any info about the negative effect of tobacco use on TKIs?