Dr. Cortes would welcome a study. There is no money to conduct a scientific trial. Until "Curcumin" can be patented, there is no incentive for any drug company to sponsor a trial. So research that is done using Curcumin is usually in Academic research settings (NIH grants) and not specific to a particular disease necessarily. The only study I am aware involving Sprycel and Curcumin was in colon cancer (where the positive correlation was reported).
We would need to have a similar trial done using Sprycel + Curcumin on a statistically meaningful sample of CML patients. Dr. Cortes is willing to do this.
In the mean time, I am my own study. I do believe there is a correlation (strong one in fact), but it is my opinion and it is not scientific. The good news is that after more than a year on high dose Curcumin (even with low platelets during some of this time period), I have had only positive effects (arthritis, etc.). So I know, for me, it is safe to take. But Curcumin is not a panacea. Some researchers point out that Curcumin in high dose can have some negative effects:
Trey points out that the down regulating affect Curcumin has on many cell processes can't be all good.
The effects, in my view, are minor in comparison with the benefits and then can be monitored (iron chelation). And since CML (and cancer in general) is a runaway cell process - some downregulating is just fine with me. And it is not clear just how much Curcumin one would have to ingest to get these negative effects given Curcumin's generally low bio-availability.
Still - it is important to note everything we can find out about whatever we take. Too much water can kill you too.
I take Curcumin. I take 8 grams of it every day. My skin is better for it. My joints are better for it. And my Sprycel is taken in a lower dose because of it (my view; jury still out on this one).
It hasn't changed my sex life though. Wife still runs away when I go hunting.
Diagnosed 11 May 2011 (100% FiSH, 155% PCR)
with b2a2 BCR-ABL fusion transcript coding for the 210kDa BCR-ABL protein
Sprycel: 20 mg per day - taken at lights out with Quercetin and/or Magnesium Taurate
6-8 grams Curcumin C3 complex.
2015 PCR: < 0.01% (M.D. Anderson scale)
2016 PCR: < 0.01% (M.D. Anderson scale)
March 2017 PCR: 0.01% (M.D. Anderson scale)
June 2017 PCR: "undetected"
September 2017 PCR: "undetected"