Advanced Member
Posted 09 March 2013 - 06:33 AM
Hello.
A great subject for a Saturday morning, diarrhea.
I took my 4x100mg pills of Gleevec as usual this morning, but around 15 minutes after i took it, i had to run to the bathroom where i had a case of diarrhea.
After around 1 hour i noticed how great i was feeling, and i didnt have that "regular" fuzzy gleevec feeling.
So, i took another 2x100mg pills just to be safe, does this sound like the right thing to do in a case like this?
Have a great weekend.
Teddy.
Advanced Member
Posted 09 March 2013 - 07:40 AM
Teddy,
If I had had a vicious case of vomiting perhaps I would have taken another full dose, but, if I didn't find 4 totally undigested Gleevec pills in my stool, I would have left well enough alone for one day. : )
Pat
Pat
"You can't change the direction of the wind but you can adjust your sails."
DX 12/08; Gleevec 400mg; liver toxicity; Sprycel 100mg.; CCyR 4/10; MMR 8/10; Pleural Effusion 2/12; Sprycel 50mg. Maintaining MMR; 2/15 PCRU; 8/16 drifting in and out of undetected like a wave meeting the shore. Retired 12/23/2016! 18 months of PCRU, most recent at Mayo on 7/25/17 was negative at their new sensitivity reporting of 0.003.<p>
Advanced Member
Posted 09 March 2013 - 10:47 AM
Hey Pat.
Luckily I didnt look for traces of pills in my stools
Yeah, i guess it shouldnt be a problem, but i dont want to give the cml any chance of coming back.
Worst case i only get 200mg dose today, best case i get 600mg, but i highly doubt that, given that i feel pretty damn good today. (Even after a bottle of wine yesterday)
Teddy
Advanced Member
Posted 09 March 2013 - 05:31 PM
Teddy,
I have been on 400mg of Gleevec for little over a year now. Thats been my routine every morning. I eat breakfast then take the G and hid to the bathroom and get cleaned out. I never have seen the pills in it, I don't know if they float thou.... lol A couple of hours later I am light headed and ready for another meal.
Flo
1 2012 CML detected Started Gleevec 400 mg
In nov 2014 my pcr started to rise by Feb I stopped Gleevec and went onto
2 2015 Tasigna 600 mg/day
I have been PCRU for 2 years and stopped Tasigna 4 7 2017
5 8 2017 results 0.008
5 30 2017 results 0.028
6 30 2017 results 0.3, I have restarted the Tasigna because it went above 0.1
My son
11 2011 CML detected Started Gleevec 400 mg
He went 2 1/2 years on gleevec and lost PCRU
Started Sprycel went PCRU for 2 years and stopped the Sprycel, went back for 3 month checkup and PCR was 8.0
He went back onto Sprycel and now is PCRU again
3 16 2017 results 0.008
6 1 2017 results 0.002
Advanced Member
Posted 09 March 2013 - 08:13 PM
Hi: Are you on 400mg a day, but taking 4/100mg pills? If that is the case then maybe you should take 2/100mg pills in the morning with a full breakfast first which might help diarrhea or anything else. Then take the other 2/100mg pills with your dinner. How long have you been on Gleevec? I am on it 12 years, and in the beginning I had the nausea if I did not eat a full meal before taking my pill. It still happens to me if I do not eat enough food occasionally. I did not experience any bowel problems that I can remember.
Maybe I did not follow your post correctly, but that is how I understood it.
Susan
Advanced Member
Posted 10 March 2013 - 03:42 AM
Hey Floa7, hehe, yeah, usually thats my routine as well, but this time, well, it was mostly "water" that came out (what a dreaful subject), and i didnt get my regular Gleevec feeling which i have had every day since i started taking these pills.
Susan: Indeed taking 4x100mg for easier swallowing.
I have thought about splitting dosage, but i think this is the first time i have had stomach issues right after taking the pills. I blame it on the wine, and the fact that i drank a lot of more water than i usually do when taking the pills (almost tripple the normal amount)
Seems to be working well today at least
0 members, 1 guests, 0 anonymous users
