I have been taking Gleevec 400mg for about 1.5 years now. About 3 weeks ago I started experiencing twitching in my legs, and it has since moved to my toes,fingers and arms. Has anyone else had this happen while on Gleevec? I've had muscle cramps before, but this is different. The twitch only lasts a second and doesn't hurt, but it has become very annoying. I have also been having a burning feeling in both legs, but this is not constant and has only happened a few times. The doctor told me to try and up my potassium as it was on the low side of normal, however, after eating 2 bananas every day for a week, it hasn't helped. I am calling him back today, but I was wondering if anyone has any other advice?