I went to th doctor last year due to a swollen cyst in my thyroid. WBC-12.7 k/ul, Lymphocyte absolute 3.7 k/ul, Granulocytes absolute 8.3 k/ul, platelet 455 k/ul, ESR 63 mm/hr.
Abnormal Blood Tests
Posted 22 August 2012 - 02:05 PM
Posted 22 August 2012 - 02:39 PM
What were you BASO numbers?
Posted 22 August 2012 - 05:19 PM
I guess I'm wondering what your question is. ( Never mind, I didn't see your previous post! Sorry!)
"You can't change the direction of the wind but you can adjust your sails."
DX 12/08; Gleevec 400mg; liver toxicity; Sprycel 100mg.; CCyR 4/10; MMR 8/10; Pleural Effusion 2/12; Sprycel 50mg. Maintaining MMR; 2/15 PCRU; 8/16 drifting in and out of undetected like a wave meeting the shore. Retired 12/23/2016! 18 months of PCRU, most recent at Mayo on 7/25/17 was negative at their new sensitivity reporting of 0.003.<p>
Posted 23 August 2012 - 12:32 AM
Posted 24 August 2012 - 12:09 PM
That low Baso number would make me think that CML is not the issue. I'm not a doctor so don't go by what I say, but typically CML presents with higher Baso.
Posted 24 August 2012 - 01:01 PM
My Basophils were always normal and I have CML. Regards, Frank
Posted 24 August 2012 - 03:38 PM
That is interesting, mine were elevated and the doctor who diagnosed me had said he thought it was CML based on my CBC because my basophils were high and that was typically an indication of CML.
I also had read the following
"CML is often suspected on the basis on the complete blood count, which shows increased granulocytes of all types, typically including mature myeloid cells. Basophilsand eosinophils are almost universally increased; this feature may help differentiate CML from a leukemoid reaction. A bone marrow biopsy is often performed as part of the evaluation for CML, and CML is diagnosed by detecting the Philadelphia chromosome. This characteristic chromosomal abnormality can be detected by routinecytogenetics, by fluorescent in situ hybridization, or by PCR for the bcr-abl fusion gene."
Posted 24 August 2012 - 04:42 PM
I guess I'm the exception! Frank
Posted 24 August 2012 - 06:45 PM
Frank - you most definitely ARE exceptional!
Dx: Sudden severe anemia detected 07/2011, followed by WBC spike. CML Dx 02/2012.
Rx: 03/2012-Gleevec400. Reduced 02/2013 to Gleevec300 due to side effects (low blood counts).
Response: PCR-Und within 7 mo. on G400. Maintained MMR4-MMR4.5 on G300. PCR-Und since 02/2016.
Posted 24 August 2012 - 07:03 PM
Thanks! I'll try to convince my wife! Regards, Frank
Posted 24 August 2012 - 08:31 PM
Naw, you've got company, Frank. My basophils were normal, too.
We can be exceptional together!
Posted 24 August 2012 - 11:06 PM
Now I have some hematology trivia questions for my onc next visit.
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